Rv0433

Tuberculist information
Gene nameRv0433
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)520.324
Molecular mass(da)42277.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 376
	  		  	1    LPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRN   60
			  	61   TVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYA  120
			  	121  ELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTG  180
			  	181  YASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLE  240
			  	241  VRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAV  300
			  	301  IILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHD  360
			  	361  GDLRAVVDALVAELVI

Known structures in the PDB
No Known structures
1 38 75 112 149 186 223 260 297 334 371 Range: 20 to 297  |  Coverage: 73% GCS2 Range: 11 to 368  |  Coverage: 94% 1 Range: 8 to 375  |  Coverage: 97% 1
Number of amino acids : 376
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
GCS2PF0410720-297
Mtb Structural Proteome models
Model Number1
Model nameRv0433
Template1R8G    APDBCREDO
Template coverage5_363
Template Identity(%)28.0
Model coverage(%)94.9
Normalized DOPE score-0.517

Structure Models from Chopin
Model Number1
Profiled.128.1.3
Click for model details
zscore62.4
Residue begin8
Residue end375
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0433Gene nameConfidence Score
Rv0431Rv04310.956
Rv0434Rv04340.946
Rv0430Rv04300.942
Rv0432sodC0.932
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions