Rv0117

Tuberculist information
Gene nameoxyS
Protein functionOxidative stress response regulatory protein OxyS
Functional category(tuberculist)regulatory proteins
Gene location(kb)141.2
Molecular mass(da)34191.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 314
	  		  	1    VLFRQLEYFVAVAQERHFARAAEKCYVSQPALSSAIAKLERELNVTLINRGHSFEGLTRE   60
			  	61   GERLVVWAKRILAEHAAFKAEVDAVRSGITGTLRLGTVPTASTTASLVLSAFCSAHPLAK  120
			  	121  VQVCSRLAATELYRRLREFELDAVIVHPETQDSDDVDLVPLYEEQYVLLSPADMLPPGTS  180
			  	181  TLVWRDAAQLPLALLTADMRDRQVIDAAFADHAVSAIPQVETDSVASLFAQVATGNWASI  240
			  	241  VPHTWLWAMPMSGPTGGEIRAVELVDPVLKAQIALATNALGPGSPVARALITCAQALALN  300
			  	301  EFFDTQLRGITRRR

Known structures in the PDB
No Known structures
1 32 63 94 125 156 187 218 249 280 311 Range: 3 to 62  |  Coverage: 18% HTH_1 Range: 86 to 299  |  Coverage: 67% LysR_substrate Range: 1 to 300  |  Coverage: 95% 1 Range: 1 to 89  |  Coverage: 28% 1
Number of amino acids : 314
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
HTH_1PF001263-62
LysR_substratePF0346686-299
Mtb Structural Proteome models
Model Number1
Model nameRv0117
Template1IXC    APDBCREDO
Template coverage1_294
Template Identity(%)21.5
Model coverage(%)95.2
Normalized DOPE score-0.215

Structure Models from Chopin
Model Number1
Profilea.4.5.37
Click for model details
zscore15.9
Residue begin1
Residue end89
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0117Gene nameConfidence Score
Rv1908ckatG0.99
Rv2428ahpC0.966
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions