Rv3724B

Tuberculist information
Gene namecut5b
Protein functionProbable cutinase [second part] Cut5b
Functional category(tuberculist)cell wall and cell processes
Gene location(kb)4169.61
Molecular mass(da)18755.2
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 187
	  		  	1    VAPGSHLVLAASEDCSSTHCVSQVGAKSLGVYAVNYPASNDFASSDFPKTVIDGIRDAGS   60
			  	61   HIQSMAMSCPQTRQVLGGYSQGAAVAGYVTSAVVPPAVPVQAVPAPMAPEVANHVAAVTL  120
			  	121  FGAPSAQFLGQYGAPPIAIGPLYQPKTLQLCADGDSICGDGNSPVAHGLYAVNGMVGQGA  180
			  	181  NFAASRL

Known structures in the PDB
No Known structures
1 19 37 55 73 91 109 127 145 163 181 Range: 6 to 187  |  Coverage: 96% Cutinase Range: 7 to 187  |  Coverage: 96% 1
Number of amino acids : 187
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
CutinasePF010836-187
Mtb Structural Proteome models
Model Number1
Model nameRv3724B
Template1QOZ    APDBCREDO
Template coverage14_206
Template Identity(%)24.3
Model coverage(%)95.7
Normalized DOPE score-0.117

Structure Models from Chopin
CHOPIN models not available for this query
Binding pockets
STRING
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Protein interacting with Rv3724BGene nameConfidence Score
Rv3724Acut5a0.964
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions