SInCRe - Rv3630

Tuberculist information

Gene name	Rv3630
Protein function	Probable conserved integral membrane protein
Functional category(tuberculist)	cell wall and cell processes
Gene location(kb)	4069.18
Molecular mass(da)	43467.1
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 431

	  		  	1    LAVGAAAVTEVGDTASPVGSSGASGGAIASGSVARVGTAAAVTALCGYAVIYLAARNLAP   60
			  	61   NGFSVFGVFWGAFGLVTGAANGLLQETTREVRSLGYLDVSADGRRTHPLRVSGMVGLGSL  120
			  	121  VVIAGSSPLWSGRVFAEARWLSVALLSIGLAGFCLHATLLGMLAGTNRWTQYGALMVADA  180
			  	181  VIRVVVAAATFVIGWQLVGFIWATVAGSVAWLIMLMTSPPTRAAARLMTPGATATFLRGA  240
			  	241  AHSIIAAGASAILVMGFPVLLKLTSNELGAQGGVVILAVTLTRAPLLVPLTAMQGNLIAH  300
			  	301  FVDERTERIRALIAPAALIGGVGAVGMLAAGVVGPWIMRVAFGSEYQSSSALLAWLTAAA  360
			  	361  VAIAMLTLTGAAAVAAALHRAYSLGWVGATVGSGLLLLLPLSLETRTVVALLCGPLVGIG  420
			  	421  VHLVALARTDE

Known structures in the PDB

No Known structures

Number of amino acids : 431

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
MatE	PF01554	42-184

Mtb Structural Proteome models

Structure models not available for this query

Structure Models from Chopin

CHOPIN models not available for this query

Binding pockets

Structure models not available for this query

STRING

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Protein interacting with Rv3630	Gene name	Confidence Score
Rv0403c	mmpS1	0.903

Potential ligand/drug binding sites

No binding sites identified

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

No high confidence interactions