Rv3485c

Tuberculist information
Gene nameRv3485c
Protein functionProbable short-chain type dehydrogenase/reductase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3904.62
Molecular mass(da)33193.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 314
	  		  	1    MNSRAPRNLAVSSPSAQVTGRMVQNGENLFQFRREGPQVQLSFQDRTYLVTGGGSGIGKG   60
			  	61   VAAGLVAAGAAVMIVGRNPDKLAAAVKDIEALKTGAIGYEPADITDEEQTLRVVDAATAW  120
			  	121  HGRLHGVVHCAGGSQTIGPITQIDSQAWRRTVDLNVNGTMYVLKHAARELVRGGGGSFVG  180
			  	181  ISSIAASNTHRWFGAYGVTKSAVDHMMKLAADELGPSWVRVNSIRPGLIRTDLVVPVTES  240
			  	241  PELSADYRVCTPLPRVGEVEDVANLAMFLLSDAASWITGQVINVDGGHMLRRGPDFSPML  300
			  	301  EPVFGADGLRGVVG

Known structures in the PDB
No Known structures
1 32 63 94 125 156 187 218 249 280 311 Range: 52 to 289  |  Coverage: 75% adh_short_C2 Range: 18 to 312  |  Coverage: 93% 1 Range: 1 to 314  |  Coverage: 99% 1
Number of amino acids : 314
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
adh_short_C2PF1356152-289
Mtb Structural Proteome models
Model Number1
Model nameRv3485c
Template1W6U    APDBCREDO
Template coverage35_328
Template Identity(%)28.8
Model coverage(%)93.6
Normalized DOPE score-0.037

Structure Models from Chopin
Model Number1
Profilec.2.1.2 - 3.40.50.720
Click for model details
zscore18.28
Residue begin1
Residue end314
Binding pockets
STRING
STRING interactions not available for this query
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions