Rv3228

Tuberculist information
Gene nameRv3228
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)3604.73
Molecular mass(da)34857.8
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 330
	  		  	1    LRPGDYDESDVKVRSGRSSRPRTKTRPEHADAEAAMVVSVDRGRWGCVLGGRPDRRITAM   60
			  	61   RARELGRTPIVVGDDVDVVGDLSGRPDTLARIVRRAPRRTVLRRTADDTDPTERVVVANA  120
			  	121  DQLLIVVALADPPPRTGLVDRALIAAYAGGLTPILCLTKTDLAPAEPFGKQFADLELTVT  180
			  	181  AAGVDDPLLAVADLLAGKITVLLGHSGVGKSTLVNRLVPEADRAVGEVTEIGRGRHTSTR  240
			  	241  SVALPLGDTLSGSGWVIDTPGIRSFGLAHIQPDNVLLAFSDLAEATRECPRGCGHMGPPA  300
			  	301  DPECALDTLSGPAARRAAAARRLLAVLSQT

Known structures in the PDB
No Known structures
1 34 67 100 133 166 199 232 265 298 331 Range: 165 to 325  |  Coverage: 48% DUF258 Range: 32 to 327  |  Coverage: 89% 1 Range: 267 to 330  |  Coverage: 19% 1
Number of amino acids : 330
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DUF258PF03193165-325
Mtb Structural Proteome models
Model Number1
Model nameRv3228
Template1U0L    APDBCREDO
Template coverage4_289
Template Identity(%)25.6
Model coverage(%)89.1
Normalized DOPE score0.33

Structure Models from Chopin
Model Number1
Profile1.10.40.50
Click for model details
zscore11.76
Residue begin267
Residue end330
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv3228Gene nameConfidence Score
Rv3227aroA0.98
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
zincPubChem0.76565.409