Rv2894c

Tuberculist information
Gene namexerC
Protein functionProbable integrase/recombinase XerC
Functional category(tuberculist)Insertion seqs and phages
Gene location(kb)3203.39
Molecular mass(da)31947.6
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 298
	  		  	1    VQAILDEFDEYLALQCGRSVHTRRAYLGDLRSLFAFLADRGSSLDALTLSVLRSWLAATA   60
			  	61   GAGAARTTLARRTSAVKAFTAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMA  120
			  	121  AAESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRTV  180
			  	181  PFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVHQTVAAVDGAPD  240
			  	241  MGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA

Known structures in the PDB
No Known structures
1 30 59 88 117 146 175 204 233 262 291 Range: 5 to 87  |  Coverage: 27% Phage_integr_N Range: 108 to 286  |  Coverage: 59% Phage_integrase Range: 5 to 292  |  Coverage: 96% 1 Range: 1 to 298  |  Coverage: 99% 1 Range: 105 to 286  |  Coverage: 60% 2 Range: 1 to 111  |  Coverage: 36% 3
Number of amino acids : 298
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Phage_integr_NPF028995-87
Phage_integrasePF00589108-286
Mtb Structural Proteome models
Model Number1
Model nameRv2894c
Template1A0P    APDBCREDO
Template coverage8_292
Template Identity(%)39.9
Model coverage(%)96.3
Normalized DOPE score0.191

Structure Models from Chopin
Model Number1
Profilea.60.9.1, d.163.1.1 - 1.10.150.130, 1.10.443.10
Click for model details
zscore41.59
Residue begin1
Residue end298
Model Number2
Profile1.10.443.10
Click for model details
zscore17.24
Residue begin105
Residue end286
Model Number3
Profile1.10.150.130
Click for model details
zscore15.17
Residue begin1
Residue end111
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2894cGene nameConfidence Score
Rv3646ctopA0.935
Rv3646ctopA0.935
Rv3646ctopA0.935
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions