Rv2766c

Tuberculist information
Gene nameRv2766c
Protein functionProbable short-chain type dehydrogenase/reductase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)3075.59
Molecular mass(da)27140.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 260
	  		  	1    MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVLTARRQEAADEAAAQVGDRALGVG   60
			  	61   AHAVDEDAARRCVDLTLERFGSVDILINNAGTNPAYGPLLEQDHARFAKIFDVNLWAPLM  120
			  	121  WTSLVVTAWMGEHGGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPRIRVN  180
			  	181  AICPGVVRTRLAEALWKDHEDPLAATIALGRIGEPADIASAVAFLVSDAASWITGETMII  240
			  	241  DGGLLLGNALGFRAAPSTEH

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 15 to 245  |  Coverage: 88% adh_short_C2 Range: 7 to 243  |  Coverage: 90% 1 Range: 1 to 260  |  Coverage: 99% 1
Number of amino acids : 260
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
adh_short_C2PF1356115-245
Mtb Structural Proteome models
Model Number1
Model nameRv2766c
Template1IY8    APDBCREDO
Template coverage12_262
Template Identity(%)36.7
Model coverage(%)90.8
Normalized DOPE score-0.635

Structure Models from Chopin
Model Number1
Profilec.2.1.2 - 3.40.50.720
Click for model details
zscore21.34
Residue begin1
Residue end260
Binding pockets
STRING
STRING interactions not available for this query
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions