Rv2717c

Tuberculist information
Gene nameRv2717c
Protein functionConserved protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)3029.87
Molecular mass(da)17846.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 164
	  		  	1    MTRDLAPALQALSPLLGSWAGRGAGKYPTIRPFEYLEEVVFAHVGKPFLTYTQQTRAVAD   60
			  	61   GKPLHSETGYLRVCRPGCVELVLAHPSGITEIEVGTYSVTGDVIELELSTRADGSIGLAP  120
			  	121  TAKEVTALDRSYRIDGDELSYSLQMRAVGQPLQDHLAAVLHRQR

Known structures in the PDB
PDB ID2FR2
Total residue count172
Number of chains1
MethodX-RAY
Resolution1.5
1 17 33 49 65 81 97 113 129 145 161 Range: 7 to 163  |  Coverage: 95% DUF1794 Range: 4 to 164  |  Coverage: 97% 1 Range: 4 to 164  |  Coverage: 97% 2 Range: 2 to 164  |  Coverage: 98% 1
Number of amino acids : 164
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
DUF1794PF087687-163
Mtb Structural Proteome models
Model Number1
Model nameRv2717c_2fr2_A
Template2FR2    APDBCREDO
Template coverage4_164
Template Identity(%)100.0
Model coverage(%)97.6
Normalized DOPE score-1.201

Model Number2
Model nameRv2717c
Template2FR2    APDBCREDO
Template coverage4_164
Template Identity(%)100.0
Model coverage(%)97.6
Normalized DOPE score-0.942

Structure Models from Chopin
Model Number1
Profileb.60.1.8
Click for model details
zscore37.31
Residue begin2
Residue end164
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2717cGene nameConfidence Score
Rv2718cnrdR0.955
Rv2719cRv2719c0.901
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions