Rv2578c

Tuberculist information
Gene nameRv2578c
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2902.51
Molecular mass(da)37175.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 340
	  		  	1    MRWARQAVAVNGMPVDDGALPGLQRIGLVRSVRAPQFDGITFHEVLCKSALNKVPNAAAL   60
			  	61   PFRYTVNGYRGCSHACRYCFARPTHEYLDFNPGTDFDTQVVVKTNVAAVLRHELRRPSWR  120
			  	121  RETVALGTNTDPYQRAEGRYALMPGIIGALAASGTPLSILTKGTLLRRDLPLIAEAAQQV  180
			  	181  PVSVAVSLAVGDPELHRDVESGTPTPQARLALITAIRAAGLDCHVMVAPVLPQLTDSGEH  240
			  	241  LDQLLGQIAAAGATGVTVFGLHLRGSTRGWFMCWLARAHPELVSRYRELYRRGPYLPPSY  300
			  	301  REMLRERVAPLIAKYRLAGDHRPAPPETEAALVPVQATLF

Known structures in the PDB
No Known structures
1 35 69 103 137 171 205 239 273 307 341 Range: 66 to 245  |  Coverage: 52% Radical_SAM Range: 24 to 337  |  Coverage: 92% 1 Range: 126 to 294  |  Coverage: 49% 1
Number of amino acids : 340
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Radical_SAMPF0405566-245
Mtb Structural Proteome models
Model Number1
Model nameRv2578c
Template1R30    APDBCREDO
Template coverage5_304
Template Identity(%)12.7
Model coverage(%)92.1
Normalized DOPE score0.267

Structure Models from Chopin
Model Number1
Profile3.80.30.10
Click for model details
zscore9.07
Residue begin126
Residue end294
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2578cGene nameConfidence Score
Rv2579dhaA0.938
Rv3395cRv3395c0.922
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions