Rv2573

Tuberculist information
Gene nameRv2573
Protein functionConserved hypothetical protein
Functional category(tuberculist)conserved hypotheticals
Gene location(kb)2898.04
Molecular mass(da)26184
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 246
	  		  	1    VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ   60
			  	61   PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD  120
			  	121  FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV  180
			  	181  DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA  240
			  	241  ASDGPG

Known structures in the PDB
PDB ID4OL9
Total residue count304
Number of chains1
MethodX-RAY
Resolution1.85
1 25 49 73 97 121 145 169 193 217 241 Range: 5 to 149  |  Coverage: 58% ApbA Range: 169 to 291  |  Coverage: 49% ApbA_C Range: 9 to 246  |  Coverage: 96% 1 Range: 120 to 244  |  Coverage: 50% 1
Number of amino acids : 246
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
ApbAPF025585-149
ApbA_CPF08546169-291
Mtb Structural Proteome models
Model Number1
Model nameRv2573
Template2EW2    APDBCREDO
Template coverage61_311
Template Identity(%)25.6
Model coverage(%)96.3
Normalized DOPE score0.037

Structure Models from Chopin
Model Number1
Profilea.100.1.7
Click for model details
zscore23.72
Residue begin120
Residue end244
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2573Gene nameConfidence Score
Rv2225panB0.998
Rv3602cpanC0.996
Rv3601cpanD0.938
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
pantoatePubChem0.903148.157
KPLPubChem0.901146.141