Gene name | acpS |
Protein function | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrier protein]pantetheinephosphotransferase) |
Functional category(tuberculist) | lipid metabolism |
Gene location(kb) | 2839.54 |
Molecular mass(da) | 14002.8 |
External sites | TB Database TubercuList WebTB |
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PDB ID | 3H7Q | |
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Total residue count | 132 | |
Number of chains | 1 | |
Method | X-RAY | |
Resolution | 2.25 |
PDB ID | 3HQJ | |
---|---|---|
Total residue count | 130 | |
Number of chains | 1 | |
Method | X-RAY | |
Resolution | 1.95 |
PDB ID | 3NE1 | |
---|---|---|
Total residue count | 390 | |
Number of chains | 3 | |
Method | X-RAY | |
Resolution | 2.51 |
PDB ID | 3NE3 | |
---|---|---|
Total residue count | 130 | |
Number of chains | 1 | |
Method | X-RAY | |
Resolution | 1.9 |
PDB ID | 4HC6 | |
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Total residue count | 129 | |
Number of chains | 1 | |
Method | X-RAY | |
Resolution | 1.8 |
Structural/Functional domain family | Pfam acc.no./SCOP ID | Domain Region | |
---|---|---|---|
ACPS | PF01648 | 5-125 |
Model Number | 1 |
Profile | d.150.1.2 - 3.90.470.20 Click for model details |
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zscore | 20.5 |
Residue begin | 1 |
Residue end | 130 |
Protein Model | Pocket Number | Drug Binding Site | PMIN Score | Pvalue PMIN | PMAX Score | Pvalue PMAX |
---|---|---|---|---|---|---|
Rv2523c_3hqj_A | 6 | 1hwi_115_D_3PDBCREDO | 0.578 | 0.206 | 0.578 | 0.003 |
Rv2523c_3hqj_A | 6 | 1hwi_115_B_1PDBCREDO | 0.577 | 0.208 | 0.577 | 0.003 |
Rv2523c_3hqj_A | 6 | 1uob_PNN_A_1311PDBCREDO | 0.617 | 0.159 | 0.563 | 0.004 |
Rv2523c_3hqj_A | 6 | 3uvv_T3_A_501PDBCREDO | 0.571 | 0.215 | 0.554 | 0.005 |
Rv2523c_3hqj_A | 6 | 1xzx_T3_X_500PDBCREDO | 0.571 | 0.216 | 0.553 | 0.005 |
Rv2523c_3hqj_A | 6 | 1bsx_T3_A_1PDBCREDO | 0.586 | 0.196 | 0.550 | 0.005 |
Rv2523c_3hqj_A | 6 | 1bsx_T3_B_2PDBCREDO | 0.586 | 0.196 | 0.550 | 0.005 |
Rv2523c_3hqj_A | 6 | 3tkd_CYZ_A_266PDBCREDO | 0.545 | 0.252 | 0.545 | 0.005 |
Rv2523c_3hqj_A | 6 | 3gws_T3_X_500PDBCREDO | 0.580 | 0.204 | 0.544 | 0.006 |
Rv2523c_3hqj_A | 6 | 2h79_T3_A_1PDBCREDO | 0.596 | 0.184 | 0.541 | 0.006 |
Rv2523c_3hqj_A | 6 | 2h77_T3_A_1PDBCREDO | 0.607 | 0.170 | 0.533 | 0.007 |
Rv2523c_3hqj_A | 6 | 3hec_STI_A_1PDBCREDO | 0.532 | 0.269 | 0.532 | 0.007 |
Rv2523c_3hqj_A | 6 | 1hwk_117_D_3PDBCREDO | 0.566 | 0.222 | 0.532 | 0.007 |
Rv2523c_3hqj_A | 6 | 1hwl_FBI_B_1PDBCREDO | 0.576 | 0.209 | 0.525 | 0.007 |
Rv2523c_3hqj_A | 6 | 1hwl_FBI_D_3PDBCREDO | 0.575 | 0.210 | 0.525 | 0.007 |
Rv2523c_3hqj_A | 6 | 3qt0_486_A_4PDBCREDO | 0.618 | 0.158 | 0.524 | 0.008 |
Rv2523c_3hqj_A | 6 | 1y0x_T44_X_500PDBCREDO | 0.557 | 0.234 | 0.524 | 0.008 |
Rv2523c_3hqj_A | 6 | 1hwl_FBI_A_2PDBCREDO | 0.574 | 0.212 | 0.523 | 0.008 |
Rv2523c_3hqj_A | 6 | 1hwl_FBI_C_4PDBCREDO | 0.573 | 0.212 | 0.523 | 0.008 |
Rv2523c_3hqj_A | 6 | 3tkd_CYZ_B_267PDBCREDO | 0.556 | 0.236 | 0.522 | 0.008 |
Rv2523c_3hqj_A | 6 | 1hwk_117_C_4PDBCREDO | 0.590 | 0.191 | 0.522 | 0.008 |
Rv2523c_3hqj_A | 6 | 1hwk_117_A_2PDBCREDO | 0.589 | 0.193 | 0.521 | 0.008 |
Rv2523c_3hqj_A | 6 | 1hwi_115_A_2PDBCREDO | 0.572 | 0.214 | 0.519 | 0.008 |
Rv2523c_3hqj_A | 6 | 1hwk_117_B_1PDBCREDO | 0.615 | 0.161 | 0.513 | 0.009 |
Rv2523c_3hqj_A | 6 | 3gcs_BAX_A_401PDBCREDO | 0.576 | 0.209 | 0.510 | 0.009 |
Rv2523c_3hqj_A | 6 | 4asd_BAX_A_1500PDBCREDO | 0.575 | 0.210 | 0.509 | 0.009 |
Rv2523c_3hqj_A | 6 | 2y6o_1N1_A_1892PDBCREDO | 0.523 | 0.283 | 0.507 | 0.010 |
Rv2523c_3hqj_A | 6 | 3oez_STI_B_601PDBCREDO | 0.501 | 0.317 | 0.501 | 0.011 |
Rv2523c_3hqj_A | 6 | 3heg_BAX_A_1PDBCREDO | 0.549 | 0.246 | 0.500 | 0.011 |
Chemical Name | Confidence score | Molecular Weight |
---|---|---|
coenzyme APubChem | 0.998 | 767.534 |
hydron sulfatePubChem | 0.976 | 196.157 |
sulfatePubChem | 0.976 | 96.0626 |
Co-APubChem | 0.974 | 767.534 |
magnesiumPubChem | 0.963 | 24.305 |
bicinePubChem | 0.9 | 163.172 |
4'-phosphopantetheinePubChem | 0.829 | 358.348 |
glycerolPubChem | 0.78 | 92.0938 |
selenomethioninePubChem | 0.736 | 196.106 |
nonribosomal peptidePubChem | 0.712 | 972.2 |