Rv2499c

Tuberculist information
Gene nameRv2499c
Protein functionPossible oxidase regulatory-related protein
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)2813.17
Molecular mass(da)20226.9
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 185
	  		  	1    VTKHAGDRESDDAVSACRVAGSTVGRRILQRGLWFEEFQIGTTYLHRPGRTVTEADNVLF   60
			  	61   TTLTMNTQSLHLDAAWAGQQPGFRGERLVNSMFTLSTMVGLSVAQLTLGTIVANLGFSEV  120
			  	121  SFPKPVFHGDTLYAETVCTGKRESKSRPGEGIVTLEHIARNQHGEVVARAVRTTLVQKQS  180
			  	181  IKEAQ

Known structures in the PDB
No Known structures
1 19 37 55 73 91 109 127 145 163 181 Range: 36 to 161  |  Coverage: 67% MaoC_dehydratas Range: 32 to 180  |  Coverage: 80% 1 Range: 5 to 185  |  Coverage: 97% 1
Number of amino acids : 185
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
MaoC_dehydratasPF0157536-161
Mtb Structural Proteome models
Model Number1
Model nameRv2499c
Template1Q6W    APDBCREDO
Template coverage12_159
Template Identity(%)31.1
Model coverage(%)80.0
Normalized DOPE score0.072

Structure Models from Chopin
Model Number1
Profiled.38.1.4 - 3.10.129.10
Click for model details
zscore18.5
Residue begin5
Residue end185
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv2499cGene nameConfidence Score
Rv2498ccitE0.994
Rv2504cscoA0.916
Rv2502caccD10.903
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions