SInCRe - Rv2042c

Tuberculist information

Gene name	Rv2042c
Protein function	Conserved protein
Functional category(tuberculist)	conserved hypotheticals
Gene location(kb)	2287.88
Molecular mass(da)	29091.2
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 265

	  		  	1    MAPPNRDELLAAVERSPQAAAAHDRAGWVGLFTGDARVEDPVGSQPQVGHEAIGRFYDTF   60
			  	61   IGPRDITFHRDLDIVSGTVVLRDLELEVAMDSAVTVFIPAFLRYDLRPVTGEWQIAALRA  120
			  	121  YWELPAMMLQFLRTGSGATRPALQLSRALLGNQGLGGTAGFLTGFRRAGRRHKKLVETFL  180
			  	181  NAASRADKSAAYHALSRTATMTLGEDELLDIVELFEQLRGASWTKVTGAGSTVAVSLASD  240
			  	241  HRRGIMFADVPWRGNRINRIRYFPA

Known structures in the PDB

No Known structures

Number of amino acids : 265

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
NTF2	PF02136	8-130

Mtb Structural Proteome models

Model Number	1
Model name	Rv2042c
Template	2A15 APDB CREDO
Template coverage	5_134
Template Identity(%)	29.8
Model coverage(%)	46.4
Normalized DOPE score	-0.594

Structure Models from Chopin

Model Number	1
Profile	d.17.4.3 - 3.10.450.50 Click for model details
zscore	13.55
Residue begin	2
Residue end	134

Binding pockets

STRING

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Protein interacting with Rv2042c	Gene name	Confidence Score
Rv2044c	Rv2044c	0.965
Rv2043c	pncA	0.951

Potential ligand/drug binding sites

No binding sites identified

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

No high confidence interactions