Rv1856c

Tuberculist information
Gene nameRv1856c
Protein functionPossible oxidoreductase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)2104.15
Molecular mass(da)23228.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 225
	  		  	1    MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDAVVCDTTDPTS   60
			  	61   LTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAWRNALDATVLSVVLTVQSVGD  120
			  	121  HLRSGGSIVSVVAENPPAGGAESAIKAALSNWIAGQAAVFGTRGITINTVACGRSVQTGY  180
			  	181  EGLSRTPAPVAAEIARLALFLTTPAARHITGQTLHVSHGALAHFG

Known structures in the PDB
No Known structures
1 23 45 67 89 111 133 155 177 199 221 Range: 9 to 221  |  Coverage: 94% adh_short_C2 Range: 2 to 224  |  Coverage: 98% 1 Range: 1 to 225  |  Coverage: 99% 1
Number of amino acids : 225
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
adh_short_C2PF135619-221
Mtb Structural Proteome models
Model Number1
Model nameRv1856c
Template2D1Y    APDBCREDO
Template coverage6_249
Template Identity(%)25.6
Model coverage(%)98.7
Normalized DOPE score-0.919

Structure Models from Chopin
Model Number1
Profilec.2.1.2 - 3.40.50.720
Click for model details
zscore23
Residue begin1
Residue end225
Binding pockets
STRING
STRING interactions not available for this query
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions