Rv1701

Tuberculist information
Gene nameRv1701
Protein functionProbable integrase/recombinase
Functional category(tuberculist)Insertion seqs and phages
Gene location(kb)1926.2
Molecular mass(da)33517.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 311
	  		  	1    MKTLALQLQGYLDHLTIERGVAANTLSSYRRDLRRYSKHLEERGITDLAKVGEHDVSEFL   60
			  	61   VALRRGDPDSGTAALSAVSAARALIAVRGLHRFAAAEGLAELDVARAVRPPTPSRRLPKS  120
			  	121  LTIDEVLSLLEGAGGDKPSDGPLTLRNRAVLELLYSTGARISEAVGLDLDDIDTHARSVL  180
			  	181  LRGKGGKQRLVPVGRPAVHALDAYLVRGRPDLARRGRGTAAIFLNARGGRLSRQSAWQVL  240
			  	241  QDAAERAGITAGVSPHMLRHSFATHLLEGGADVRVVQELLGHASVTTTQIYTLVTVHALR  300
			  	301  EVWAGAHPRAR

Known structures in the PDB
No Known structures
1 32 63 94 125 156 187 218 249 280 311 Range: 8 to 98  |  Coverage: 28% Phage_integr_N Range: 119 to 298  |  Coverage: 57% Phage_integrase Range: 2 to 304  |  Coverage: 97% 1 Range: 2 to 310  |  Coverage: 99% 1 Range: 119 to 298  |  Coverage: 57% 2 Range: 1 to 115  |  Coverage: 36% 3
Number of amino acids : 311
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Phage_integr_NPF028998-98
Phage_integrasePF00589119-298
Mtb Structural Proteome models
Model Number1
Model nameRv1701
Template1A0P    APDBCREDO
Template coverage3_292
Template Identity(%)42.8
Model coverage(%)97.1
Normalized DOPE score-0.261

Structure Models from Chopin
Model Number1
Profilea.60.9.1, d.163.1.1 - 1.10.150.130, 1.10.443.10
Click for model details
zscore46.67
Residue begin2
Residue end310
Model Number2
Profiled.163.1.1 - 1.10.443.10
Click for model details
zscore20.58
Residue begin119
Residue end298
Model Number3
Profile1.10.150.130
Click for model details
zscore12.71
Residue begin1
Residue end115
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1701Gene nameConfidence Score
Rv3646ctopA0.972
Rv3646ctopA0.972
Rv3646ctopA0.972
Rv1700Rv17000.932
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions