Rv1688

Tuberculist information
Gene namempg
Protein functionPossible 3-methyladenine DNA glycosylase Mpg
Functional category(tuberculist)information pathways
Gene location(kb)1912.98
Molecular mass(da)21340.1
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 203
	  		  	1    MNAEELAIDPVAAAHRLLGATIAGRGVRAMVVEVEAYGGVPDGPWPDAAAHSYRGRNGRN   60
			  	61   DVMFGPPGRLYTYRSHGIHVCANVACGPDGTAAAVLLRAAAIEDGAELATSRRGQTVRAV  120
			  	121  ALARGPGNLCAALGITMADNGIDLFDPSSPVRLRLNDTHRARSGPRVGVSQAADRPWRLW  180
			  	181  LTGRPEVSAYRRSSRAPARGASD

Known structures in the PDB
No Known structures
1 21 41 61 81 101 121 141 161 181 201 Range: 2 to 186  |  Coverage: 90% Pur_DNA_glyco Range: 1 to 197  |  Coverage: 96% 1 Range: 1 to 197  |  Coverage: 96% 1
Number of amino acids : 203
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Pur_DNA_glycoPF022452-186
Mtb Structural Proteome models
Model Number1
Model nameRv1688
Template1EWN    APDBCREDO
Template coverage86_295
Template Identity(%)32.1
Model coverage(%)96.6
Normalized DOPE score-0.204

Structure Models from Chopin
Model Number1
Profileb.46.1.2 - 3.10.300.10
Click for model details
zscore39.94
Residue begin1
Residue end197
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv1688Gene nameConfidence Score
Rv1689tyrS0.968
Rv1689tyrS0.968
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
Chemical NameConfidence scoreMolecular Weight
1,N6-ethenoadeninePubChem0.958159.148
3-methyladeninePubChem0.958149.153
hypoxanthinePubChem0.957136.111