SInCRe - Rv1505c

Tuberculist information

Gene name	Rv1505c
Protein function	Conserved hypothetical protein
Functional category(tuberculist)	conserved hypotheticals
Gene location(kb)	1695.28
Molecular mass(da)	24056.3
External sites	TB Database TubercuList WebTB

Protein sequence

Number of amino acids : 221

	  		  	1    MTKPLVIFGSGDIAQLAHYYFTRDSEYEVVAFTVDRDYASVSEFCGLPLVAFDEVAQRFP   60
			  	61   PESHAMFVALAYAKLNGVRKEKYLAAKALGYELASYVSSHATVLNDGRIGENVFLLEDNT  120
			  	121  IQPFVSIGNNVTLWSGNHIGHHSTIHDHCFLASHIVVSGGVVIEEQSFIGVNATLRDHIT  180
			  	181  IGSRCVVGAGALLLGDADADGVYIGTKTERRPVPSTELRKI

Known structures in the PDB

No Known structures

Number of amino acids : 221

Domains assigned based on sequence.

Mtb Structural proteome models

CHOPIN models

Profile-based domain assignment

Structural/Functional domain family	Pfam acc.no./SCOP ID	Domain Region
Hexapep	PF00132	106-141
Hexapep	PF00132	160-195

Mtb Structural Proteome models

Model Number	1
Model name	Rv1505c
Template	1OCX APDB CREDO
Template coverage	9_181
Template Identity(%)	20.7
Model coverage(%)	75.7
Normalized DOPE score	0.273

Structure Models from Chopin

Model Number	1
Profile	b.81.1.8 Click for model details
zscore	27.49
Residue begin	1
Residue end	211

Binding pockets

STRING

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Protein interacting with Rv1505c	Gene name	Confidence Score
Rv1506c	Rv1506c	0.993
Rv1504c	Rv1504c	0.988
Rv1502	Rv1502	0.949
Rv1507c	Rv1507c	0.908

Potential ligand/drug binding sites

No binding sites identified

Similarity to known drug target from sensitive sequence analysis

No drug targets

List of small molecules tested from TIBLE

Data not available

Off-target activity - ligand based from TIBLE

Data not available

Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.

Data not available

STITCH interactions

No high confidence interactions