Rv0927c

Tuberculist information
Gene nameRv0927c
Protein functionProbable short-chain type dehydrogenase/reductase
Functional category(tuberculist)intermediary metabolism and respiration
Gene location(kb)1033.84
Molecular mass(da)26745.7
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 263
	  		  	1    MILDMFRLDDKVAVITGGGRGLGAAIALAFAQAGADVLIASRTSSELDAVAEQIRAAGRR   60
			  	61   AHTVAADLAHPEVTAQLAGQAVGAFGKLDIVVNNVGGTMPNTLLSTSTKDLADAFAFNVG  120
			  	121  TAHALTVAAVPLMLEHSGGGSVINISSTMGRLAARGFAAYGTAKAALAHYTRLAALDLCP  180
			  	181  RVRVNAIAPGSILTSALEVVAANDELRAPMEQATPLRRLGDPVDIAAAAVYLASPAGSFL  240
			  	241  TGKTLEVDGGLTFPNLDLPIPDL

Known structures in the PDB
No Known structures
1 27 53 79 105 131 157 183 209 235 261 Range: 17 to 252  |  Coverage: 89% adh_short_C2 Range: 7 to 253  |  Coverage: 93% 1 Range: 1 to 263  |  Coverage: 99% 1
Number of amino acids : 263
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
adh_short_C2PF1356117-252
Mtb Structural Proteome models
Model Number1
Model nameRv0927c
Template1GEE    APDBCREDO
Template coverage4_252
Template Identity(%)34.8
Model coverage(%)93.2
Normalized DOPE score-0.42

Structure Models from Chopin
Model Number1
Profilec.2.1.2 - 3.40.50.720
Click for model details
zscore19.91
Residue begin1
Residue end263
Binding pockets
STRING
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Protein interacting with Rv0927cGene nameConfidence Score
Rv0928pstS30.904
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions