Rv0516c

Tuberculist information
Gene nameRv0516c
Protein functionPossible anti-anti-sigma factor
Functional category(tuberculist)information pathways
Gene location(kb)608.059
Molecular mass(da)16987.4
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 158
	  		  	1    MTTTIPTSKSACSVTTRPGNAAVDYGGAQIRAYLHHLATVVTIRGEIDAANVEQISEHVR   60
			  	61   RFSLGTNPMVLDLSELSHFSGAGISLLCILDEDCRAAGVQWALVASPAVVEQLGGRCDQG  120
			  	121  EHESMFPMARSVHKALHDLADAIDRRRQLVLPLISRSA

Known structures in the PDB
No Known structures
1 16 31 46 61 76 91 106 121 136 151 Range: 29 to 135  |  Coverage: 67% STAS Range: 28 to 135  |  Coverage: 67% 1 Range: 24 to 143  |  Coverage: 75% 1
Number of amino acids : 158
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
STASPF0174029-135
Mtb Structural Proteome models
Model Number1
Model nameRv0516c
Template1VC1    APDBCREDO
Template coverage4_110
Template Identity(%)23.4
Model coverage(%)67.7
Normalized DOPE score-1.076

Structure Models from Chopin
Model Number1
Profilec.13.2.1 - 3.30.750.24
Click for model details
zscore12.35
Residue begin24
Residue end143
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0516cGene nameConfidence Score
Rv2638Rv26380.991
Rv1904Rv19040.952
Rv1743pknE0.926
Rv1743pknE0.926
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions