Rv0088

Tuberculist information
Gene nameRv0088
Protein functionPossible polyketide cyclase/dehydrase
Functional category(tuberculist)lipid metabolism
Gene location(kb)96.927
Molecular mass(da)24617.3
External sites TB Database TubercuList WebTB
Protein sequence
Number of amino acids : 224
	  		  	1    VSVYKHAPSRVRLRQTRSTVVKGRSGSLSWRRVRTGDLGLAVWGGREEYRAVKPGTPGIQ   60
			  	61   PKGDMMTVTVVDAGPGRVSRSVEVAAPAAELFAIVADPRRHRELDGSGTVRGNIKVPAKL  120
			  	121  VVGSKFSTKMKLFGLPYRITSRVTALKPNELVEWSHPLGHRWRWEFESLSPTLTRVTETF  180
			  	181  DYHAAGAIKNGLKFYEMTGFAKSNAAGIEATLAKLSDQYARGRA

Known structures in the PDB
No Known structures
1 23 45 67 89 111 133 155 177 199 221 Range: 75 to 220  |  Coverage: 64% Polyketide_cyc2 Range: 82 to 218  |  Coverage: 60% 1 Range: 74 to 224  |  Coverage: 66% 1
Number of amino acids : 224
Domains assigned based on sequence. Mtb Structural proteome models CHOPIN models
Profile-based domain assignment
Structural/Functional domain familyPfam acc.no./SCOP IDDomain Region
Polyketide_cyc2PF1060475-220
Mtb Structural Proteome models
Model Number1
Model nameRv0088
Template1XFS    APDBCREDO
Template coverage16_170
Template Identity(%)14.6
Model coverage(%)60.7
Normalized DOPE score-0.236

Structure Models from Chopin
Model Number1
Profiled.129.3.6 - 3.30.530.20
Click for model details
zscore6.8
Residue begin74
Residue end224
Binding pockets
STRING
Cytoscape Web will replace the contents of this div with protein-protein interaction network.
Protein interacting with Rv0088Gene nameConfidence Score
Rv0081Rv00810.945
Potential ligand/drug binding sites
No binding sites identified
Similarity to known drug target from sensitive sequence analysis
No drug targets
List of small molecules tested from TIBLE
Data not available
Off-target activity - ligand based from TIBLE
Data not available
Small molecules involved in protein-protein complex from TIMBAL .Proteins similar to Mtb based on sequence analysis.
Data not available
STITCH interactions  
No high confidence interactions