Download low confidence result files for predictions for 2,473 DUF families

3,087 protein families with yet unknown structure and function (DUFs/UPFs), were queried against SCOP-NrichD database, SUPFAM+ database, SUPERFAMILY database, pDomTHREADER and HHsearch against SCOP-profile database (1.75v). For 614 DUFs we provide high confidence predictions (http://proline.biochem.iisc.ernet.in/RHD_DUFS/) and for the remaining 2,473 low confidence predictions by each of the five methods for these families can be downloaded from the following links.

(1) Low confidence predictions by SCOP-NrichD database

    Results of two types of searches that were performed using HMMER3.0 package are provided here.
(a) DUF HMM profile was queried in SCOP-NrichD database using hmmsearch program at E-value 0.001 and
(b) Iterative searches for a representative query sequence for each DUF family was queried in SCOP-NrichD database at E-value of 0.001 for inclusion of hits in each iteration.

(2) Low confidence predictions by SUPFAM+ database

    Profile-profile alignment searches were performed against SCOP database and Pfam database. The low confidence result files for both these searches in Pfam and SCOP database, annotated as *.ah_scop_result and *ah_pfam_result respectively are available here. The result file reports: Hit profile name | Match score | Z-score | Query start and query end | Hit start and hit end| Query length and hit length

(3) Low confidence predictions by SUPERFAMILY database

      Low confidence hits at E-value 0.01 are provided here.

(4) Low confidence predictions by pDomTHREADER method

(5) Low confidence predictions by HHSearch method

      Low confidence hits at E-value 0.01 are provided here.