Dengue - Human protein : Indirect interactions
Human protein | Serotype | system | experiment | |
---|---|---|---|---|
ANGPTL3 Aliases: ANG-5, ANGPT5, ANL3, FHBL2 GeneCards | PubMed | DF, DHF and DSS | Patients sera | ELISA |
ATG5 Aliases: APG5, APG5-LIKE, APG5L, ASP, hAPG5 GeneCards | PubMed | DENV2 | MEF, Huh7 | Transmission electron microscopy, Immunofluorescence microscopy, Western blot, FACS |
BAX Aliases: BCL2L4 GeneCards | PubMed | DENV1 | BHK, Huh-7, Vero | TUNEL assay, FACS, Western blot, Mutational analysis |
BAX Aliases: BCL2L4 GeneCards | PubMed | DENV2 | HUVEC, EA.hy926 | Western blotting |
BCL2L1 Aliases: BCL-XL/S, BCL2L, BCLX, Bcl-X, PPP1R52 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Quantitative real-time PCR |
C5 Aliases: C5D, C5a, C5b, CPAMD4, ECLZB GeneCards | PubMed | DF, DHF and DSS | Patients sera | ELISA |
CASP8 Aliases: ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 GeneCards | PubMed | DENV2 | HUVEC | Western blot |
CASP8 Aliases: ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 GeneCards | PubMed | DENV2 | HUVEC, EA.hy926 | Western blotting |
CASP9 Aliases: APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 GeneCards | PubMed | DENV2 | HepG2 | Western blotting |
CASP9 Aliases: APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 GeneCards | PubMed | DENV2 | HUVEC, EA.hy926 | Western blotting |
CCL2 Aliases: GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF GeneCards | PubMed | DENV2 | Human microvascular endothelial cell line-1 HMEC-1, | Western blot, FACs, ELISA, RT-PCR |
CCR7 Aliases: BLR2, CC-CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1 GeneCards | PubMed | DENV2 | Human Monocyte-derived Dendritic cells | FACS |
CD4 Aliases: CD4mut GeneCards | PubMed | DF, DHF | Patients sera | ELISA |
CD73 Aliases: CALJA, CD73, E5NT, NT, NT5, NTE, eN, eNT GeneCards | PubMed | DENV2 | HUVEC | qRT-PCR, Trans-endothelial electrical resistance assays, FACS |
CD8 Aliases: CD8, Leu2, MAL, p32 GeneCards | PubMed | DF, DHF | Patients sera | ELISA |
CDH1 Aliases: Arc-1, CD324, CDHE, ECAD, LCAM, UVO GeneCards | PubMed | DENV4 | U937, MDCK | Immunofluorescence microscopy, Western blot, Transepithelial electrical resistance assay, Transmission electron microscopy, Vascular permeability assay |
CDH5 Aliases: 7B4, CD144 GeneCards | PubMed | DENV2 | Human Monocyte-derived immature dendritic cells, HUVEC | Protein array, In vitro permeability assay, In vivo vascular permeability enhancement assay, Immunofluorescence microscopy |
CDH5 Aliases: 7B4, CD144 GeneCards | PubMed | DENV2 | EA.hy926 | Western blot, Confocal Laser Scanning Microscopy |
CDH5 Aliases: 7B4, CD144 GeneCards | PubMed | DENV2, DENV4 | Human dermal fibroblasts (HDFs), Human dermal microvascular endothelial cells (HDMECs) | Leukocyte transendothelial migration assay, FACS, |
CFD Aliases: ADIPSIN, ADN, DF, PFD GeneCards | PubMed | DF, DHF | Patients sera | ELISA |
CFD Aliases: ADIPSIN, ADN, DF, PFD GeneCards | PubMed | DF, DHF and DSS | Patients sera | ELISA |
CHI3L1 Aliases: ASRT7, CGP-39, GP-39, GP39, HC-gp39, HCGP-3P, YKL-40, YKL40, YYL-40, hCGP-39 GeneCards | PubMed | DF, DHF and DSS | Patients sera | ELISA |
CISH Aliases: BACTS2, CIS, CIS-1, G18, SOCS GeneCards | PubMed | Modeling | ||
CSF2RB Aliases: CD131, CDw131, IL3RB, IL5RB, SMDP5 GeneCards | PubMed | ADE DENV2 | THP-1 | cDNA array |
CTSS Aliases: GeneCards | PubMed | DENV2 | HepG2 | siRNA, Real time RT-PCR, Lysosome permeability assay |
CXCL10 Aliases: C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 GeneCards | PubMed | DENV2 | BHK-21, Hepa1-6 | Real-time PCR, ELISA |
CXCL10 Aliases: C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic Cells, T cells, HUVEC | ELISA |
CXCL10 Aliases: C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 GeneCards | PubMed | DENV4 | HUVEC | ELISA |
CXCL10 Aliases: C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Quantitative real-time PCR |
CXCL10 Aliases: C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1 GeneCards | PubMed | DF, DHF and DSS | Patients sera | ELISA |
CXCL11 Aliases: H174, I-TAC, IP-9, IP9, SCYB11, SCYB9B, b-R1 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic Cells, T cells, HUVEC | ELISA |
CXCL11 Aliases: H174, I-TAC, IP-9, IP9, SCYB11, SCYB9B, b-R1 GeneCards | PubMed | DENV4 | HUVEC | ELISA |
CXCL9 Aliases: CMK, Humig, MIG, SCYB9, crg-10 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic Cells, T cells, HUVEC | ELISA |
EDN1 Aliases: ARCND3, ET1, HDLCQ7, PPET1, QME GeneCards | PubMed | Patients with and without plasma leakage | Patient blood samples | ELISA |
ENG Aliases: END, HHT1, ORW1 GeneCards | PubMed | DF, DHF and DSS | Patients sera | ELISA |
EPAS1 Aliases: ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Enrichment analysis of transcription factors activating the DEGs |
ERN1 Aliases: IRE1, IRE1P, IRE1a, hIRE1p GeneCards | PubMed | DENV2 | Human fibrosarcoma 2fTGH cells, MEF | Western blottting |
F2 Aliases: PT, RPRGL2, THPH1 GeneCards | PubMed | DF, DHF | Patients sera | ELISA |
F2R Aliases: CF2R, HTR, PAR-1, PAR1, TR GeneCards | PubMed | DENV2 | HUVEC | Prothrombin activation assay, FACs |
F3 Aliases: CD142, TF, TFA GeneCards | PubMed | DENV2 | HUVEC | Prothrombin activation assay, FACs |
FAS Aliases: ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 GeneCards | PubMed | DENV2 | HUVEC | qPCR, FACS |
FASL Aliases: ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6, TNLG1A GeneCards | PubMed | DENV2 | HUVEC | qPCR, FACS |
FOS Aliases: AP-1, C-FOS, p55 GeneCards | PubMed | DENV2 | 293A, HepG2 | Inhibition assay, Luciferase reporter gene assay |
FYN Aliases: SLK, SYN, p59-FYN GeneCards | PubMed | DENV2 | Huh7, 293T | Inhibition studies, siRNA |
FYN Aliases: SLK, SYN, p59-FYN GeneCards | PubMed | DENV2 | Vero | Molecular modeling, Autodock Vina docking, Glide docking, In vitro Kinase inhibition assay, viral inhibition by RT-PCR |
G6PD Aliases: G6PD1 GeneCards | PubMed | DENV2 | Primary human monocytes | FACS, Plague assay, Detection of nitric oxide, superoxide and oxidative stress |
GCLC Aliases: GCL, GCS, GLCL, GLCLC GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Quantitative real-time PCR |
GCLM Aliases: GLCLR GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Quantitative real-time PCR |
HIF1A Aliases: HIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Enrichment analysis of transcription factors activating the DEGs |
HLA-A Aliases: Aw-33, Aw-74, HLAA GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | HepG2 | RT-PCR, Western blotting |
HMOX1 Aliases: HMOX1D, HO-1, HSP32, bK286B10 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Quantitative real-time PCR |
ICAM1 Aliases: BB2, CD54, P3.58 GeneCards | PubMed | DENV2 | Human microvascular endothelial cell line-1 HMEC-1, | Western blot, FACs, ELISA, RT-PCR, Adhesion assay |
ICAM1 Aliases: BB2, CD54, P3.58 GeneCards | PubMed | DENV2 | Human microvascular endothelial cells (HMVEC) | qRT-PCR, Western blot |
ICAM1 Aliases: BB2, CD54, P3.58 GeneCards | PubMed | DHF, DENV2 | THP-1, HUVEC, DHF Patient sera | RT-PCR, ELISA, FACS |
ICAM1 Aliases: BB2, CD54, P3.58 GeneCards | PubMed | DENV2, DENV4 | Human dermal fibroblasts (HDFs), Human dermal microvascular endothelial cells (HDMECs) | Leukocyte transendothelial migration assay, FACS, |
ICAM1 Aliases: BB2, CD54, P3.58 GeneCards | PubMed | DF, DHF and DSS | Patients sera | ELISA |
IDO1 Aliases: IDO, IDO-1, INDO GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
IFIH1 Aliases: AGS7, Hlcd, IDDM19, MDA-5, MDA5, RLR-2, SGMRT1 GeneCards | PubMed | ADE DENV2 | THP-1 | Western blotting |
IFIH1 Aliases: AGS7, Hlcd, IDDM19, MDA-5, MDA5, RLR-2, SGMRT1 GeneCards | PubMed | DENV2, DENV4 | A549, BHK-21 | siRNA, RT-PCR, Western blot |
IFIH1 Aliases: AGS7, Hlcd, IDDM19, MDA-5, MDA5, RLR-2, SGMRT1 GeneCards | PubMed | DENV1 | Macrophages, Huh-7 and shRIG-I cells | RT-PCR, siRNA, Western blot, ELISA, Immunofluorescence microscopy |
IFITM1 Aliases: 9-27, CD225, DSPA2a, IFI17, LEU13 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
IFNA1 Aliases: IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@ GeneCards | PubMed | DENV2 | Human Myeloid Dendritic Cells | ELISA |
IFNA1 Aliases: IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@ GeneCards | PubMed | DENV2 | Human Monocyte-derived dendritic cells | FACs |
IFNA1 Aliases: IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA13, IFNA@ GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
IFNA2 Aliases: IFN-alphaA, IFNA, IFNA2B, INFA2 GeneCards | PubMed | DENV2 | Human foreskin fibroblasts HFF, HepG2, K562, THP-1 | Competitive asymmetric reverse transcriptase-mediated PCR (RT-PCR), FACs, Plaque assay |
IFNA2 Aliases: IFN-alphaA, IFNA, IFNA2B, INFA2 GeneCards | PubMed | DENV2 | Human Myeloid Dendritic Cells | ELISA |
IFNA2 Aliases: IFN-alphaA, IFNA, IFNA2B, INFA2 GeneCards | PubMed | DENV2 | Human Monocyte-derived dendritic cells | FACs |
IFNA2 Aliases: IFN-alphaA, IFNA, IFNA2B, INFA2 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
IL10 Aliases: CSIF, GVHDS, IL-10, IL10A, TGIF GeneCards | PubMed | DENV2 | Human Monocyte-derived dendritic cells, Human Peripheral blood T cells | FACs, ELISA, T cell proliferation assay |
IL10 Aliases: CSIF, GVHDS, IL-10, IL10A, TGIF GeneCards | PubMed | DENV2 | THP-1 | Antibody-dependent enhancement (ADE) infection assay, ELISA |
IL10 Aliases: CSIF, GVHDS, IL-10, IL10A, TGIF GeneCards | PubMed | ADE DENV2 | THP-1 | ELISA |
IL10 Aliases: CSIF, GVHDS, IL-10, IL10A, TGIF GeneCards | PubMed | DENV3 | Human bone-marrow–derived dendritic cells | qPCR |
IL10RA Aliases: CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R GeneCards | PubMed | ADE DENV2 | THP-1 | cDNA array |
IL12A Aliases: CLMF, IL-12A, NFSK, NKSF1, P35 GeneCards | PubMed | DENV2 | THP-1 | Antibody-dependent enhancement (ADE) infection assay, ELISA |
IL12A Aliases: CLMF, IL-12A, NFSK, NKSF1, P35 GeneCards | PubMed | DENV2 | Human bone-marrow–derived dendritic cells | qPCR |
IL12A Aliases: CLMF, IL-12A, NFSK, NKSF1, P35 GeneCards | PubMed | DENV4 | U937, MDCK | BD cytometric bead array |
IL12B Aliases: CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2 GeneCards | PubMed | DENV2 | THP-1 | Antibody-dependent enhancement (ADE) infection assay, ELISA |
IL12B Aliases: CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2 GeneCards | PubMed | DENV2 | Human bone-marrow–derived dendritic cells | qPCR |
IL12B Aliases: CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2 GeneCards | PubMed | DENV4 | U937, MDCK | BD cytometric bead array |
IL18RAP Aliases: ACPL, CD218b, CDw218b, IL-18R-beta, IL-18RAcP, IL-18Rbeta, IL-1R-7, IL-1R7, IL-1RAcPL, IL18RB GeneCards | PubMed | DF, DHF and DSS | Patients sera | ELISA |
IL2 Aliases: IL-2, TCGF, lymphokine GeneCards | PubMed | DF, DHF | Patients sera | ELISA |
IL2 Aliases: IL-2, TCGF, lymphokine GeneCards | PubMed | DENV2 | Human Monocyte-derived dendritic cells, Human Peripheral blood T cells | FACs, ELISA, T cell proliferation assay |
IL2RA Aliases: CD25, IDDM10, IL2R, IMD41, TCGFR, p55 GeneCards | PubMed | DF, DHF | Patients sera | ELISA |
IL4 Aliases: BCGF-1, BCGF1, BSF-1, BSF1, IL-4 GeneCards | PubMed | DENV2 | Human Monocyte-derived dendritic cells, Human Peripheral blood T cells | FACs, ELISA, T cell proliferation assay |
IL7 Aliases: IL-7 GeneCards | PubMed | DENV4 | HUVEC | ELISA |
IRF9 Aliases: IRF-9, ISGF3, ISGF3G, p48 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Enrichment analysis of transcription factors activating the DEGs |
JAK2 Aliases: JTK10, THCYT3 GeneCards | PubMed | DENV2 | HepG2 | EMSA, Western blotting |
JAK3 Aliases: JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK GeneCards | PubMed | DENV2 | HepG2 | EMSA, Western blotting |
JNK Aliases: JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c GeneCards | PubMed | DENV2 | Human Monocyte-derived macrophages | Indirect immunofluorescence microscopy, Western blot, Inhibition assay |
JUN Aliases: AP-1, AP1, c-Jun GeneCards | PubMed | DENV2 | 293A, HepG2 | Inhibition assay, Luciferase reporter gene assay |
JUN Aliases: AP-1, AP1, c-Jun GeneCards | PubMed | DENV2 | Human Monocyte-derived macrophages | Indirect immunofluorescence microscopy, Western blot, Inhibition assay |
KDR Aliases: CD309, FLK1, VEGFR, VEGFR2 GeneCards | PubMed | DF, DHF and DSS | Patients sera | ELISA |
LGALS9 Aliases: HUAT, LGALS9A GeneCards | PubMed | DENV2 | Human monocyte derived Dendritic cells, gamma-delta T cells | qRT-PCR, Western blot, FACS, siRNA, Inhibition studies |
MAPK1 Aliases: ERK, ERK-2, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK GeneCards | PubMed | DENV2 | HUVEC | Western blot, Inhibition studies |
MAPK11 Aliases: P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta GeneCards | PubMed | DENV2 | Human Monocyte-derived macrophages | Indirect immunofluorescence microscopy, Western blot, Inhibition assay |
MAPK11 Aliases: P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta GeneCards | PubMed | DENV2 | Human monocyte derived Dendritic cells, gamma-delta T cells | Inhibition studies |
MAPK14 Aliases: CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA GeneCards | PubMed | DENV2 | HUVEC | Western blot, Inhibition studies |
MAPK14 Aliases: CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA GeneCards | PubMed | DENV2 | Human Monocyte-derived macrophages | Indirect immunofluorescence microscopy, Western blot, Inhibition assay |
MAPK14 Aliases: CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA GeneCards | PubMed | DENV2 | HepG2 | siRNA |
MAPK14 Aliases: CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA GeneCards | PubMed | Human PBMCs, THP-1, KU812 | Inhibition studies | |
MAPK14 Aliases: CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA GeneCards | PubMed | DENV2 | Human monocyte derived Dendritic cells, gamma-delta T cells | Inhibition studies |
MAPK3 Aliases: ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK GeneCards | PubMed | DENV2 | HUVEC | Western blot, Inhibition studies |
MIR30E Aliases: MIRN30E, mir-30e GeneCards | PubMed | DENV1, DENV2, DENV3 | U937 | siRNA, qRT-PCR |
MMP2 Aliases: CLG4, CLG4A, MMP-2, MMP-II, MONA, TBE-1 GeneCards | PubMed | DENV2 | Human Monocyte-derived immature dendritic cells, HUVEC | Protein array, In vitro permeability assay, In vivo vascular permeability enhancement assay, Immunofluorescence microscopy |
MMP2 Aliases: CLG4, CLG4A, MMP-2, MMP-II, MONA, TBE-1 GeneCards | PubMed | Patients with and without plasma leakage | Patient blood samples | ELISA |
MMP2 Aliases: CLG4, CLG4A, MMP-2, MMP-II, MONA, TBE-1 GeneCards | PubMed | DENV2 | LLC/MK2 | RT-PCR, Gelatinolytic activity assay |
MMP9 Aliases: CLG4B, GELB, MANDP2, MMP-9 GeneCards | PubMed | DENV2 | Human Monocyte-derived immature dendritic cells, HUVEC | Protein array, In vitro permeability assay, In vivo vascular permeability enhancement assay, Immunofluorescence microscopy |
MMP9 Aliases: CLG4B, GELB, MANDP2, MMP-9 GeneCards | PubMed | DENV2 | U937 | Western blot, Gelatin zymography, Semi-quantitative RT-PCR |
MMP9 Aliases: CLG4B, GELB, MANDP2, MMP-9 GeneCards | PubMed | DENV2 | LLC/MK2 | RT-PCR, Gelatinolytic activity assay |
NFE2L2 Aliases: HEBP1, NRF2 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Enrichment analysis of transcription factors activating the DEGs |
NFKB1 Aliases: CVID12, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 GeneCards | PubMed | DENV1 | HepG2 | Immunofluorescence microscopy, Western blot, EMSA |
NFKB1 Aliases: CVID12, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 GeneCards | PubMed | DENV2 | Human neuroblastoma cell line SK-N-SH | NF-kB activation assay |
NFKB1 Aliases: CVID12, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 GeneCards | PubMed | DENV2 | 293A | Inhibition assay, Luciferase reporter gene assay |
NFKB1 Aliases: CVID12, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 GeneCards | PubMed | DENV2 | HUVEC | Immunofluorscence microscopy |
NFKB1 Aliases: CVID12, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 GeneCards | PubMed | DENV2 | Human Monocyte-derived Dendritic cells | EMSA |
NFKB1 Aliases: CVID12, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 GeneCards | PubMed | DENV2 | Human bone-marrow–derived dendritic cells | Luciferase reporter assay, Immunofluorescence microscopy |
NFKB1 Aliases: CVID12, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Enrichment analysis of transcription factors activating the DEGs |
NFKB1 Aliases: CVID12, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 GeneCards | PubMed | DENV2 | RAW264.7 | Western blot, Luciferase reporter assay, Immunofluorescence microscopy, Inhibition studies |
NFKB2 Aliases: CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p100, p49/p100, p52 GeneCards | PubMed | DENV2 | Human neuroblastoma cell line SK-N-SH | NF-kB activation assay |
NFKB2 Aliases: CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p100, p49/p100, p52 GeneCards | PubMed | DENV2 | RAW264.7 | Western blot, Luciferase reporter assay, Immunofluorescence microscopy, Inhibition studies |
NQO1 Aliases: DHQU, DIA4, DTD, NMOR1, NMORI, QR1 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Quantitative real-time PCR |
ACACA Aliases: ACACD, ACC, ACC1, ACCA, ACACA GeneCards | PubMed | DENV2 | Huh-7.5, 293T | siRNA |
ACTR2 Aliases: ARP2 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
ADM Aliases: AM, PAMP GeneCards | PubMed | DENV2 | Huh7, AG129 | ISG inhibition assays |
AKT1 Aliases: AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA GeneCards | PubMed | DENV2 | BHK | Western blotting |
ALPK3 Aliases: MAK, MIDORI GeneCards | PubMed | DENV2 | Huh7 | siRNA |
AMPH Aliases: AMPH1 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
ANGPT1 Aliases: AGP1, AGPT, ANG1 GeneCards | PubMed | DENV2 | HUVEC | SemiqRT-PCR, Western blot analysis |
ANGPT1 Aliases: AGP1, AGPT, ANG1 GeneCards | PubMed | DF, DHF and DSS | Patients sera | ELISA |
ANGPT2 Aliases: AGPT2, ANG2 GeneCards | PubMed | DENV2 | HUVEC | SemiqRT-PCR, Western blot analysis |
ANGPT2 Aliases: AGPT2, ANG2 GeneCards | PubMed | Patients with and without plasma leakage | Patients sera | ELISA |
ANLN Aliases: FSGS8, Scraps, scra GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
AP1B1 Aliases: ADTB1, AP105A, BAM22, CLAPB2 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
AP1M1 Aliases: AP47, CLAPM2, CLTNM, MU-1A GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7 | siRNA, Binding assay, Real time RT-PCR |
AP2A1 Aliases: ADTAA, AP2-ALPHA, CLAPA1 GeneCards | PubMed | DENV2 | ECV304, Vero | Western blot, Confocal Laser Scanning Microscopy |
AP2A1 Aliases: ADTAA, AP2-ALPHA, CLAPA1 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
AP2B1 Aliases: ADTB2, AP105B, AP2-BETA, CLAPB1 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
AP2M1 Aliases: AP50, CLAPM1, mu2 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
APOA1 Aliases: GeneCards | PubMed | DENV2 | Vero, AD-293, Huh-7, HepG2 | Co-immunoprecipitation, siRNA, FACs analysis after virus absorption |
APOE Aliases: AD2, APO-E, LDLCQ5, LPG GeneCards | PubMed | Structure and sequence comparison | ||
ARPC1B Aliases: ARC41, p40-ARC, p41-ARC GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
ARPC3 Aliases: ARC21, p21-Arc GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
ARRB1 Aliases: ARB1, ARR1 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
ATF6 Aliases: ATF6A GeneCards | PubMed | DENV1, DENV2 | A549 | Western blot, RT-PCR, inhibition assays |
ATF6 Aliases: ATF6A GeneCards | PubMed | DENV2 | Huh-7.5, 293T | siRNA |
ATF6 Aliases: ATF6A GeneCards | PubMed | DENV2 | Human fibrosarcoma 2fTGH cells, MEF | Western blottting |
ATG12 Aliases: APG12, APG12L, FBR93, HAPG12 GeneCards | PubMed | ADE DENV2 | THP-1 | Western blotting |
ATG12 Aliases: APG12, APG12L, FBR93, HAPG12 GeneCards | PubMed | DENV2 | Huh-7.5, 293T | siRNA |
ATP6AP1 Aliases: 16A, ATP6IP1, ATP6S1, Ac45, CF2, VATPS1, XAP-3, XAP3 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
ATP6AP1 Aliases: 16A, ATP6IP1, ATP6S1, Ac45, CF2, VATPS1, XAP-3, XAP3 GeneCards | PubMed | DENV2, DENV3, DENV4 | HeLa | Western blot, siRNA |
ATP6AP2 Aliases: APT6M8-9, ATP6IP2, ATP6M8-9, ELDF10, HT028, M8-9, MRXE, MRXSH, MSTP009, PRR, RENR, XMRE, XPDS GeneCards | PubMed | DENV2 | Huh7 | siRNA |
ATP6V0A1 Aliases: ATP6N1, ATP6N1A, Stv1, VPP1, Vph1, a1 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
ATP6V0B Aliases: ATP6F, HATPL, VMA16 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
ATP6V0C Aliases: ATP6C, ATP6L, ATPL, VATL, VPPC, Vma3 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
ATP6V0D1 Aliases: ATP6D, ATP6DV, P39, VATX, VMA6, VPATPD GeneCards | PubMed | DENV2 | Huh7 | siRNA |
ATP6V1B1 Aliases: ATP6B1, RTA1B, VATB, VMA2, VPP3 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
ATP6V1B2 Aliases: ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
ATP6V1C2 Aliases: ATP6C2, VMA5 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
ATP6V1G2 Aliases: ATP6G, ATP6G2, NG38, VMA10 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
ATP6V1G3 Aliases: ATP6G3, Vma10 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
ATP6V1H Aliases: CGI-11, MSTP042, NBP1, SFD, SFDalpha, SFDbeta, VMA13 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
AVPR1B Aliases: AVPR3 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
AXL Aliases: ARK, JTK11, Tyro7, UFO GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | 293T, CHO745, Cos-7, A549, Vero, Huh7 5.1 | Cell-Binding Assay, siRNA, Immunofluroscence assay |
BBC3 Aliases: JFY-1, JFY1, PUMA GeneCards | PubMed | DENV2 | HepG2 | Real time PCR |
BCL2 Aliases: Bcl-2, PPP1R50 GeneCards | PubMed | DENV2 | BHK | Western blotting |
BCL2 Aliases: Bcl-2, PPP1R50 GeneCards | PubMed | DENV2 | HUVEC, EA.hy926 | Western blotting |
BST2 Aliases: CD317, TETHERIN GeneCards | PubMed | DENV2 | Huh7 | Overexpression studies |
CAMK1 Aliases: CAMKI GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
CAPRIN1 Aliases: GPIAP1, GPIP137, GRIP137, M11S1, RNG105, p137GPI GeneCards | PubMed | DENV2 | HuH-7 | siRNA, Western blotting, |
CASP1 Aliases: ICE, IL1BC, P45 GeneCards | PubMed | DENV1 | p53-deficient H1299, Huh7 | siRNA, Real time RT-PCR |
CASP1 Aliases: ICE, IL1BC, P45 GeneCards | PubMed | DENV2 | Human Monocyte derived macrophages (MDMs) | Inhibition studies |
CASP1 Aliases: ICE, IL1BC, P45 GeneCards | PubMed | DENV2 | Primary human monocytes | qRT-PCR, Western blotting |
CASP3 Aliases: CPP32, CPP32B, SCA-1 GeneCards | PubMed | DENV2 | HUVEC | Western blot |
CASP3 Aliases: CPP32, CPP32B, SCA-1 GeneCards | PubMed | DENV2 | HepG2 | Western blotting |
CASP3 Aliases: CPP32, CPP32B, SCA-1 GeneCards | PubMed | DENV2 | BHK | Western blotting |
CASP3 Aliases: CPP32, CPP32B, SCA-1 GeneCards | PubMed | DENV2 | HUVEC, EA.hy926 | Western blotting |
CBL Aliases: C-CBL2, FRA11B, NSLL, RNF55, CBL GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
CBLB Aliases: Cbl-b, Nbla00127, RNF56 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
CBLC Aliases: CBL-3, CBL-SL, RNF57 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
CCL3 Aliases: G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 GeneCards | PubMed | DENV2 | HepG2, Monocyte-derived dendritic cells (MDDCs) | ELISA, Quantitative RT-PCR |
CCL4 Aliases: ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 GeneCards | PubMed | DENV2 | HepG2, Monocyte-derived dendritic cells (MDDCs) | ELISA, Quantitative RT-PCR |
CCL5 Aliases: D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP GeneCards | PubMed | DENV2, DSS | EA.hy926, Patient's sera | RT-PCR, ELISA |
CCL5 Aliases: D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP GeneCards | PubMed | DENV2, DENV3 | Chang liver cells, HuH7, Hep3B | ELISA, RT-PCR |
CCL5 Aliases: D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP GeneCards | PubMed | DENV2 | HepG2, Monocyte-derived dendritic cells (MDDCs) | ELISA, Quantitative RT-PCR |
CCL5 Aliases: D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP GeneCards | PubMed | DENV2 | HepG2 | ELISA |
CCL5 Aliases: D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP GeneCards | PubMed | DENV4 | HUVEC | ELISA |
CCL5 Aliases: D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
CCL5 Aliases: D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP GeneCards | PubMed | DENV2, DENV4 | Human dermal fibroblasts (HDFs), Human dermal microvascular endothelial cells (HDMECs) | Cytokine/chemokine quantification assay |
CCR5 Aliases: CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 GeneCards | PubMed | DENV2 | THP1, C57BL/6 | qRT-PCR, ELISA, Immunofluorescence microscopy |
CD14 Aliases: GeneCards | PubMed | DENV2 | Primary Human Monocytes and Macrophages | Inhibition studies against entry using Monoclonal antibodies |
CD14 Aliases: GeneCards | PubMed | DENV2 | Human monocytes from PBMCs of healthy donors | siRNA |
CD9 Aliases: BTCC-1, DRAP-27, MIC3, MRP-1, TSPAN-29, TSPAN29 GeneCards | PubMed | DENV2 | Huh7, AG129 | ISG inhibition assays |
CDC27 Aliases: ANAPC3, APC3Hs, D0S1430E, D17S978E, H-NUC, HNUC, NUC2, CDC27 GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
CDC42 Aliases: CDC42Hs, G25K GeneCards | PubMed | DENV2 | HMEC-1 | Virus binding assay, FACS, Time-lapse fluorescent microscopy |
CDC42 Aliases: CDC42Hs, G25K GeneCards | PubMed | DENV2 | Huh-7.5, 293T | siRNA |
CDKN3 Aliases: CDI1, CIP2, KAP, KAP1 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
CEBPB Aliases: C/EBP-beta, IL6DBP, NF-IL6, TCF5 GeneCards | PubMed | DENV2, DENV3 | Chang liver cells, HuH7, Hep3B | EMSA |
CEBPB Aliases: C/EBP-beta, IL6DBP, NF-IL6, TCF5 GeneCards | PubMed | ADE DENV2 | THP-1 | cDNA array |
CHRNA2 Aliases: GeneCards | PubMed | DENV2 | Huh7 | siRNA |
CIB2 Aliases: DFNB48, KIP2, USH1J GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
CLEC5A Aliases: CLECSF5, MDL-1, MDL1 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Human Macrophage, Mice | Western blot, Confocal microscopy, FACS, ELISA |
CLEC5A Aliases: CLECSF5, MDL-1, MDL1 GeneCards | PubMed | DENV2 | Human Monocyte derived macrophages (MDMs) | Western blot, Co-immunoprecipitation |
CLTB Aliases: LCB GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
CLTC Aliases: CHC, CHC17, CLH-17L2, Hc, CLTC GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
CLTC Aliases: CHC, CHC17, CLH-17L2, Hc, CLTC GeneCards | PubMed | DENV2 | Human monocytes from PBMCs of healthy donors | siRNA |
CLTC Aliases: CHC, CHC17, CLH-17L2, Hc, CLTC GeneCards | PubMed | DENV2 | HepG2 | siRNA |
CNOT2 Aliases: CDC36, HSPC131, NOT2, NOT2H GeneCards | PubMed | DENV2 | Huh7 | siRNA |
COPB2 Aliases: beta'-COP GeneCards | PubMed | DENV2 | Huh7 | siRNA |
CRP Aliases: PTX1 GeneCards | PubMed | DENV2, DENV3, DENV4 | Serum of DF and DHF patient | ELISA |
CRP Aliases: PTX1 GeneCards | PubMed | ADE DENV2 | THP-1 | cDNA array |
CRP Aliases: PTX1 GeneCards | PubMed | DF, DHF and DSS | Patients sera | ELISA |
CSNK1D Aliases: ASPS, CKIdelta, FASPS2, HCKID GeneCards | PubMed | DENV2 | Huh7 | siRNA |
CTSB Aliases: APPS, CPSB GeneCards | PubMed | DENV2 | HepG2 | siRNA, Real time RT-PCR, Lysosome permeability assay |
CTSD Aliases: CLN10, CPSD, HEL-S-130P GeneCards | PubMed | DENV3 | HepG2 | Co-localization studies through Confocal microscopy |
CXCL8 Aliases: GCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 GeneCards | PubMed | DENV2, DSS | EA.hy926, Patient's sera | RT-PCR, ELISA |
CXCL8 Aliases: GCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 GeneCards | PubMed | DENV2 | Human dermal microvascular endothelial cell line HMEC-1 | FACs, Permeability measurements, ELISA |
CXCL8 Aliases: GCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 GeneCards | PubMed | DF Grade I, DF Grade II | Serial blood samples | ELISA |
CXCL8 Aliases: GCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 GeneCards | PubMed | DENV2 | Human microvascular endothelial cell line-1 HMEC-1, | Western blot, FACs, ELISA, RT-PCR |
CXCL8 Aliases: GCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 GeneCards | PubMed | DENV2 | 293A, HepG2 | ELISA, Inhibition assay |
CXCL8 Aliases: GCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 GeneCards | PubMed | DENV2 | HUVEC | ELISA |
CXCL8 Aliases: GCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 GeneCards | PubMed | DENV2 | HepG2 | ELISA |
DCST2 Aliases: GeneCards | PubMed | DENV2 | Huh7 | siRNA |
DDIT3 Aliases: CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 GeneCards | PubMed | DENV2 | Human fibrosarcoma 2fTGH cells, MEF | Western blottting |
DDIT3 Aliases: CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 GeneCards | PubMed | DENV2 | HepG2 | Real time PCR |
DDX3X Aliases: CAP-Rf, DBX, DDX14, DDX3, HLP2 GeneCards | PubMed | DENV2 | 293T | Real-time RT-PCR |
DDX58 Aliases: RIG-I, RIGI, RLR-1, SGMRT2 GeneCards | PubMed | DENV2 | A549 | Western blotting |
DDX58 Aliases: RIG-I, RIGI, RLR-1, SGMRT2 GeneCards | PubMed | ADE DENV2 | THP-1 | Western blotting |
DDX58 Aliases: RIG-I, RIGI, RLR-1, SGMRT2 GeneCards | PubMed | DENV2, DENV4 | A549, BHK-21 | siRNA, RT-PCR, Western blot |
DDX58 Aliases: RIG-I, RIGI, RLR-1, SGMRT2 GeneCards | PubMed | DENV1 | Macrophages, Huh-7 and shRIG-I cells | RT-PCR, siRNA, Western blot, ELISA, Immunofluorescence microscopy |
DDX58 Aliases: RIG-I, RIGI, RLR-1, SGMRT2 GeneCards | PubMed | DENV2 | Huh7, AG129 | ISG inhibition assays |
DDX58 Aliases: RIG-I, RIGI, RLR-1, SGMRT2 GeneCards | PubMed | DENV2 | Human brain microvascular endothelial cells (HBMEC) | Real time RT-PCR, siRNA |
DDX58 Aliases: RIG-I, RIGI, RLR-1, SGMRT2 GeneCards | PubMed | DENV2 | HuH-7 | Real-time RT-PCR, Western blotting, ISRE-luciferase reporter assay |
DDX58 Aliases: RIG-I, RIGI, RLR-1, SGMRT2 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
DIAPH1 Aliases: DFNA1, DIA1, DRF1, LFHL1, hDIA1 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
DIAPH1 Aliases: DFNA1, DIA1, DRF1, LFHL1, hDIA1 GeneCards | PubMed | DENV2 | Huh-7.5, 293T | siRNA |
DIAPH3 Aliases: AN, AUNA1, DIA2, DRF3, NSDAN, diap3, mDia2 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
DLL1 Aliases: DELTA1, DL1, Delta GeneCards | PubMed | DENV1, DENV2, DENV3 | Macrophages and Dendritic cells from differentiating Human PBMCs and CD4+ T cells | Real time RT-PCR |
DLL4 Aliases: hdelta2 GeneCards | PubMed | DENV1, DENV2, DENV3 | Macrophages and Dendritic cells from differentiating Human PBMCs and CD4+ T cells | Real time RT-PCR |
DNM1 Aliases: DNM, EIEE31 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
DNM2 Aliases: CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
DNM2 Aliases: CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5 GeneCards | PubMed | DENV2 | Human monocytes from PBMCs of healthy donors | siRNA |
DNM2 Aliases: CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5 GeneCards | PubMed | DENV2 | HepG2 | siRNA |
DRD4 Aliases: D4DR GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | 293, HeLa | Inhibition assay, siRNA |
DST Aliases: BP240, BPA, BPAG1, CATX-15, CATX15, D6S1101, DMH, DT, EBSB2, HSAN6, MACF2 GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
EEA1 Aliases: MST105, MSTP105, ZFYVE2 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
EGR1 Aliases: AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225 GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
EIF2AK1 Aliases: HCR, HRI GeneCards | PubMed | DENV2 | Huh7 | siRNA |
EIF2AK3 Aliases: PEK, PERK, WRS GeneCards | PubMed | DENV2 | Human fibrosarcoma 2fTGH cells, MEF | Western blottting |
EIF2AK3 Aliases: PEK, PERK, WRS GeneCards | PubMed | DENV2 | Huh7 | siRNA |
EIF2S1 Aliases: EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A GeneCards | PubMed | DENV1, DENV2 | A549 | Western blot, RT-PCR, inhibition assays |
EIF2S1 Aliases: EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A GeneCards | PubMed | DENV2 | Human fibrosarcoma 2fTGH cells, MEF | Western blottting |
EIF2S1 Aliases: EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A GeneCards | PubMed | DENV2 | A549 | Western blot |
EIF3A Aliases: EIF3, EIF3S10, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185 GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
EIF5B Aliases: IF2 GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
ELP2 Aliases: SHINC-2, STATIP1, StIP GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
ENO1 Aliases: ENO1L1, MPB1, NNE, PPH GeneCards | PubMed | DENV2 | HepG2 | Real-time PCR, 2D-PAGE, western blot, ELISA |
EPN1 Aliases: GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
EPN2 Aliases: EHB21 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
EPS15 Aliases: AF-1P, AF1P, MLLT5 GeneCards | PubMed | DENV2 | ECV304, Vero | Co-localization studies through Confocal microscopy, Inhibition studies, siRNA |
EPS15 Aliases: AF-1P, AF1P, MLLT5 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
ERC1 Aliases: Cast2, ELKS, ERC-1, RAB6IP2 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
ETNK2 Aliases: EKI2, HMFT1716 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
EXOC7 Aliases: 2-5-3p, EX070, EXO70, EXOC1, Exo70p, YJL085W GeneCards | PubMed | DENV2 | HepG2 | Real time RT-PCR, Immuno-fluorescence assay, Transmission electron microscopy |
FASTKD5 Aliases: dJ1187M17.5 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
FCGR3A Aliases: CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3, IMD20 GeneCards | PubMed | DENV2 | Patient blood samples, PBMCs | FACS |
FDFT1 Aliases: DGPT, ERG9, SQS, SS GeneCards | PubMed | DENV2 | A549, K562 | siRNA, Inhibition studies |
FES Aliases: FPS GeneCards | PubMed | DENV2 | Huh7 | siRNA |
FH Aliases: FMRD, HLRCC, LRCC, MCL, MCUL1 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
G3BP1 Aliases: G3BP, HDH-VIII GeneCards | PubMed | DENV2 | HuH-7 | siRNA, Western blotting, |
G3BP1 Aliases: G3BP, HDH-VIII GeneCards | PubMed | DENV2 | A549 | siRNA, Western blot, Indirect immunofluorescence microscopy |
G3BP2 Aliases: GeneCards | PubMed | DENV2 | HuH-7 | siRNA, Western blotting, |
GALNT10 Aliases: GALNACT10, PPGALNACT10, PPGANTASE10 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
GANAB Aliases: G2AN, GLUII GeneCards | PubMed | DENV2 | Huh7 | siRNA |
GBP1 Aliases: GeneCards | PubMed | DENV2 | RAW264.7 | qRT-PCR, Western blot, siRNA |
GCH1 Aliases: DYT14, DYT5, DYT5a, GCH, GTP-CH-1, GTPCH1, HPABH4B GeneCards | PubMed | DENV2 | Huh7 | siRNA |
GNB2L1 Aliases: Gnb2-rs1, H12.3, HLC-7, PIG21, RACK1 GeneCards | PubMed | DENV2 | Huh-7.5, 293T | siRNA |
GORASP1 Aliases: GOLPH5, GRASP65, P65 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
GSX1 Aliases: GSH1, Gsh-1 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
HAVCR1 Aliases: CD365, HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | 293T, CHO745, Cos-7, A549, Vero, Huh7 5.1 | Cell-Binding Assay, siRNA, Immunofluroscence assay |
HIP1 Aliases: HIP-I, ILWEQ, SHON, SHONbeta, SHONgamma GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
HIP1R Aliases: HIP12, HIP3, ILWEQ GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
HK2 Aliases: HKII, HXK2 GeneCards | PubMed | DENV2 | Primary human foreskin fibroblasts (HFFs) | Western blotting, qRT-PCR |
HLA-B Aliases: AS, HLAB, SPDA1 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | HepG2 | RT-PCR, Western blotting |
HLA-DRB1 Aliases: DRB1, DRw10, HLA-DR1B, HLA-DRB, SS1 GeneCards | PubMed | DENV2 | Patient blood samples, PBMCs | FACS |
HMGB1 Aliases: HMG1, HMG3, SBP-1 GeneCards | PubMed | DENV2 | A549 | Western blotting |
HMGB1 Aliases: HMG1, HMG3, SBP-1 GeneCards | PubMed | DENV2 | Primary human dendritic cells, CD3+ T cells | Immunofluorescence staining, ELISA |
HMGB1 Aliases: HMG1, HMG3, SBP-1 GeneCards | PubMed | Patients sera | ELISA | |
HMGCR Aliases: LDLCQ3 GeneCards | PubMed | DENV2, DENV3 | Huh7 | Western blotting, Immunofluorescence microscopy |
HMGCS1 Aliases: HMGCS GeneCards | PubMed | DENV2 | A549, K562 | siRNA, Inhibition studies |
HNRNPH1 Aliases: HNRPH, HNRPH1, hnRNPH GeneCards | PubMed | DENV2 | THP-1 | Proteomic analysis, siRNA, FACs, |
HPSE Aliases: HPA, HPA1, HPR11, HSE1, HPSE GeneCards | PubMed | DENV2 | Huh7, AG129 | ISG inhibition assays |
HPX Aliases: HX GeneCards | PubMed | Patients sera | Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry, ELISA, Western blotting | |
HRNR Aliases: FLG3, S100A16, S100a18 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
HSP90AA1 Aliases: EL52, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP-2, LAP2 GeneCards | PubMed | DENV2 | U937, Monocyte derived macrophages (MDMs) | Virus overlay protein binding assay, Affinity chromatography followed by MALDI, His tag pull down assay |
HSPA4 Aliases: APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY GeneCards | PubMed | DENV2 | THP-1 | siRNA, Real time RT-PCR |
HSPA5 Aliases: BIP, GRP78, HEL-S-89n, MIF2 GeneCards | PubMed | DENV2 | HepG2 | Viral overlay protein binding assay, Mass Spectrometry fingerprinting |
HSPA5 Aliases: BIP, GRP78, HEL-S-89n, MIF2 GeneCards | PubMed | DENV2 | K562, 293 | 2DE-PAGE followed by Mass spectrometry |
HSPA5 Aliases: BIP, GRP78, HEL-S-89n, MIF2 GeneCards | PubMed | DENV2 | Human fibrosarcoma 2fTGH cells, MEF | Western blottting |
HSPA5 Aliases: BIP, GRP78, HEL-S-89n, MIF2 GeneCards | PubMed | DENV2 | HepG2 | siRNA |
HSPA5 Aliases: BIP, GRP78, HEL-S-89n, MIF2 GeneCards | PubMed | DENV2 | HepG2 | Real time PCR |
HSPD1 Aliases: CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13 GeneCards | PubMed | DENV2 | U937 | siRNA |
HTR2A Aliases: 5-HT2A, HTR2 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | 293, HeLa | Inhibition assay, siRNA |
IFI6 Aliases: 6-16, FAM14C, G1P3, IFI-6-1616, IFI6 GeneCards | PubMed | DENV2 | Huh7, AG129 | ISG inhibition assays |
IFI6 Aliases: 6-16, FAM14C, G1P3, IFI-6-1616, IFI6 GeneCards | PubMed | DENV2 | HUVEC, EA.hy926 | Knockdown analysis, expression analysis |
IFIT1 Aliases: C56, G10P1, IFI-56, IFI-56K, IFI56, IFIT-1, IFNAI1, ISG56, P56, RNM561 GeneCards | PubMed | DENV2 | A549 | qRT-PCR, siRNA |
IFIT1 Aliases: C56, G10P1, IFI-56, IFI-56K, IFI56, IFIT-1, IFNAI1, ISG56, P56, RNM561 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Quantitative real-time PCR |
IFIT1 Aliases: C56, G10P1, IFI-56, IFI-56K, IFI56, IFIT-1, IFNAI1, ISG56, P56, RNM561 GeneCards | PubMed | DENV2 | HUVEC | RT-PCR |
IFIT2 Aliases: G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, P54, cig42 GeneCards | PubMed | DENV2 | A549 | qRT-PCR, siRNA |
IFIT3 Aliases: CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, P60, RIG-G, cig41 GeneCards | PubMed | DENV2 | A549 | qRT-PCR, siRNA |
IFIT5 Aliases: ISG58, P58, RI58 GeneCards | PubMed | DENV2 | A549 | qRT-PCR, siRNA |
IFITM2 Aliases: 1-8D, DSPA2c GeneCards | PubMed | DENV1 | HEK293-derived cell line FLP-IN T Rex (Invitrogen) | Overexpression studies, siRNA studies |
IFITM2 Aliases: 1-8D, DSPA2c GeneCards | PubMed | DENV2 | Huh7, AG129 | ISG inhibition assays |
IFITM2 Aliases: 1-8D, DSPA2c GeneCards | PubMed | DENV2 | HuH-7 | Real-time RT-PCR, Western blotting, ISRE-luciferase reporter assay |
IFITM2 Aliases: 1-8D, DSPA2c GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
IFITM3 Aliases: 1-8U, DSPA2b, IP15 GeneCards | PubMed | DENV1 | HEK293-derived cell line FLP-IN T Rex (Invitrogen) | Overexpression studies, siRNA studies |
IFITM3 Aliases: 1-8U, DSPA2b, IP15 GeneCards | PubMed | DENV2 | Huh7, AG129 | ISG inhibition assays |
IFITM3 Aliases: 1-8U, DSPA2b, IP15 GeneCards | PubMed | DENV2 | A549, HeLa, MDCK, 293T | Immunoprecipitation, Affinity purification coupled to mass spectroscopy, Mutation analysis |
IFITM3 Aliases: 1-8U, DSPA2b, IP15 GeneCards | PubMed | DENV2 | THP-1, A549, Huh7, 293T, U937, HepG2, HeLa, BHK-21 | Knockdown analysis, expression analysis |
IFITM3 Aliases: 1-8U, DSPA2b, IP15 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
IFNB1 Aliases: IFB, IFF, IFNB GeneCards | PubMed | DENV2 | Human foreskin fibroblasts HFF, HepG2, K562, THP-1 | Competitive asymmetric reverse transcriptase-mediated PCR (RT-PCR), FACs, Plaque assay |
IFNB1 Aliases: IFB, IFF, IFNB GeneCards | PubMed | DENV2, DENV3 | HepG2, K562 | viral RNA quantification by RT-PCR, viral plaque assays, Biosynthetic labeling and immunoprecipitation |
IFNB1 Aliases: IFB, IFF, IFNB GeneCards | PubMed | ADE DENV2 | THP-1 | ELISA |
IFNB1 Aliases: IFB, IFF, IFNB GeneCards | PubMed | DENV2 | HepG2 | RT-PCR, Immunofluorescence microscopy |
IFNB1 Aliases: IFB, IFF, IFNB GeneCards | PubMed | DENV2 | Human bone-marrow–derived dendritic cells | qPCR |
IFNB1 Aliases: IFB, IFF, IFNB GeneCards | PubMed | DENV1, DENV2, DENV3 | U937 | qRT-PCR, ELISA |
IFNB1 Aliases: IFB, IFF, IFNB GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
IFNB1 Aliases: IFB, IFF, IFNB GeneCards | PubMed | DENV2 | HUVEC | IFN-b blocking studies |
IFNG Aliases: IFG, IFI GeneCards | PubMed | DF, DHF | Patients sera | RIA |
IFNG Aliases: IFG, IFI GeneCards | PubMed | DENV2 | Human Myeloid Dendritic Cells | ELISA |
IFNG Aliases: IFG, IFI GeneCards | PubMed | DENV2, DENV3 | HepG2, K562 | viral RNA quantification by RT-PCR, viral plaque assays, Biosynthetic labeling and immunoprecipitation |
IFNG Aliases: IFG, IFI GeneCards | PubMed | DENV2 | Human Monocyte-derived dendritic cells, Human Peripheral blood T cells | FACs, ELISA, T cell proliferation assay |
IFNG Aliases: IFG, IFI GeneCards | PubMed | DENV2 | THP-1 | Antibody-dependent enhancement (ADE) infection assay, ELISA |
IFNLR1 Aliases: CRF2/12, IFNLR, IL-28R1, IL28RA, LICR2 GeneCards | PubMed | DENV2 | Huh7, AG129 | ISG inhibition assays |
IL18 Aliases: IGIF, IL-18, IL-1g, IL1F4 GeneCards | PubMed | DENV2 | Human Monocyte derived macrophages (MDMs) | ELISA, Western blotting |
IL18 Aliases: IGIF, IL-18, IL-1g, IL1F4 GeneCards | PubMed | DENV1 | Human blood derived Dendritic cells, gamma-delta T cells | ELISA |
IL1B Aliases: IL-1, IL1-BETA, IL1F2 GeneCards | PubMed | DENV2 | Human Monocyte derived macrophages (MDMs) | ELISA, Western blotting |
IL1B Aliases: IL-1, IL1-BETA, IL1F2 GeneCards | PubMed | DENV2 | Primary human monocytes | ELISA |
IL1B Aliases: IL-1, IL1-BETA, IL1F2 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
IL1B Aliases: IL-1, IL1-BETA, IL1F2 GeneCards | PubMed | DENV2 | Human primary monocytes | Real-time PCR, Western blot |
IL6 Aliases: BSF2, HGF, HSF, IFNB2, IL-6 GeneCards | PubMed | DF Grade I, DF Grade II | Serial blood samples | ELISA |
IL6 Aliases: BSF2, HGF, HSF, IFNB2, IL-6 GeneCards | PubMed | DENV2 | Human microvascular endothelial cell line-1 HMEC-1, | Western blot, FACs, ELISA, RT-PCR |
IL6 Aliases: BSF2, HGF, HSF, IFNB2, IL-6 GeneCards | PubMed | DENV2 | THP-1 | Antibody-dependent enhancement (ADE) infection assay, ELISA |
IL6 Aliases: BSF2, HGF, HSF, IFNB2, IL-6 GeneCards | PubMed | DENV2, DENV3, DENV4 | Serum of DF and DHF patient | ELISA |
IL6 Aliases: BSF2, HGF, HSF, IFNB2, IL-6 GeneCards | PubMed | DENV4 | HUVEC | ELISA |
IL6 Aliases: BSF2, HGF, HSF, IFNB2, IL-6 GeneCards | PubMed | DENV4 | U937, MDCK | BD cytometric bead array |
IL6 Aliases: BSF2, HGF, HSF, IFNB2, IL-6 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
IRF1 Aliases: IRF-1, MAR GeneCards | PubMed | DENV2 | A549 | Western blotting |
IRF1 Aliases: IRF-1, MAR GeneCards | PubMed | DENV2 | THP-1 | Antibody-dependent enhancement (ADE) infection assay, ELISA |
IRF1 Aliases: IRF-1, MAR GeneCards | PubMed | ADE DENV2 | THP-1 | cDNA array |
IRF1 Aliases: IRF-1, MAR GeneCards | PubMed | DENV2 | Huh7, AG129 | ISG inhibition assays |
IRF1 Aliases: IRF-1, MAR GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Enrichment analysis of transcription factors activating the DEGs |
IRF3 Aliases: GeneCards | PubMed | DENV2 | A549 | Western blotting |
IRF3 Aliases: GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Enrichment analysis of transcription factors activating the DEGs |
IRF7 Aliases: IMD39, IRF-7HA, IRF7B, IRF7C, IRF7H, IRF7 GeneCards | PubMed | DENV2 | A549 | Western blotting |
IRF7 Aliases: IMD39, IRF-7HA, IRF7B, IRF7C, IRF7H, IRF7 GeneCards | PubMed | DENV2 | Huh7, AG129 | ISG inhibition assays |
IRF7 Aliases: IMD39, IRF-7HA, IRF7B, IRF7C, IRF7H, IRF7 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Enrichment analysis of transcription factors activating the DEGs |
ISG15 Aliases: G1P2, IFI15, IMD38, IP17, UCRP, hUCRP GeneCards | PubMed | DENV2 | HeLa, 293T | Overexpression studies, siRNA studies |
ISG15 Aliases: G1P2, IFI15, IMD38, IP17, UCRP, hUCRP GeneCards | PubMed | DENV2 | HuH-7 | Real-time RT-PCR, Western blotting, ISRE-luciferase reporter assay |
ITGB3 Aliases: BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT GeneCards | PubMed | DENV2 | HMEC-1 | FACS, Real time RT-PCR |
ITSN2 Aliases: PRO2015, SH3D1B, SH3P18, SWA, SWAP GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
LCP2 Aliases: SLP-76, SLP76 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
LDLR Aliases: FH, FHC, LDLCQ2 GeneCards | PubMed | DENV2, DENV3 | Huh7 | Western blotting, Immunofluorescence microscopy |
LILRB1 Aliases: CD85J, ILT-2, ILT2, LIR-1, LIR1, MIR-7, MIR7 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | THP-1 | Competition binding assay, siRNA, Overexpression analysis |
LRIG3 Aliases: LIG3 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
MAK Aliases: RP62, dJ417M14.2 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
MAP1LC3A Aliases: ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3 GeneCards | PubMed | DENV2 | HepG2 | Co-localization studies through Confocal microscopy, Inhibition studies |
MAP1LC3A Aliases: ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3 GeneCards | PubMed | DENV3 | HepG2 | Co-localization studies through Confocal microscopy |
MAP4K5 Aliases: GCKR, KHS, KHS1, MAPKKKK5 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
MAPK8IP2 Aliases: IB-2, IB2, JIP2, PRKM8IPL GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
MIF Aliases: GIF, GLIF, MMIF GeneCards | PubMed | DENV2 | HMEC-1 | siRNA, ELISA |
MIF Aliases: GIF, GLIF, MMIF GeneCards | PubMed | DHF, DENV2 | THP-1, HUVEC, DHF Patient sera | RT-PCR, ELISA, FACS |
MIR146A Aliases: MIRN146, MIRN146A, miR-146a, miRNA146A GeneCards | PubMed | DENV2 | THP-1 | Real-time PCR, Northern blotting |
MIRLET7C Aliases: LET7C, MIRNLET7C, hsa-let-7c, let-7c GeneCards | PubMed | DENV2, DENV4 | Huh7 | Microarray, Real-time RT-PCR |
MMP3 Aliases: CHDS6, MMP-3, SL-1, STMY, STMY1, STR1 GeneCards | PubMed | DENV2 | RAW264.7 | qRT-PCR, Western Blot, Co-immunoprecipitation |
MUC2 Aliases: MLP, MUC-2, SMUC GeneCards | PubMed | DENV2 | Huh7 | siRNA |
MVD Aliases: FP17780, MDDase, MPD GeneCards | PubMed | DENV2 | A549, K562 | siRNA, Inhibition studies |
MX1 Aliases: IFI-78K, IFI78, MX, MxA GeneCards | PubMed | DENV2 | HuH-7 | Western blotting |
MX1 Aliases: IFI-78K, IFI78, MX, MxA GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
NAA35 Aliases: EGAP, MAK10, MAK10P, bA379P1.1 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
NACA Aliases: HSD481, skNAC, NACA GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
NAPA Aliases: SNAPA GeneCards | PubMed | DENV2 | Huh7, AG129 | ISG inhibition assays |
NEK6 Aliases: SID6-1512 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
NFKBIA Aliases: IKBA, MAD-3, NFKBI GeneCards | PubMed | DENV1, DENV2, DENV3 | U937 | Western blot, Luciferase assay |
NLRP3 Aliases: AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCAS1, FCU, MWS, NALP3, PYPAF1 GeneCards | PubMed | DENV2 | Human Monocyte derived macrophages (MDMs) | Western blot, Co-immunoprecipitation, siRNA |
NOS2 Aliases: HEP-NOS, INOS, NOSA, NOS2 GeneCards | PubMed | DENV1 | Primary monocytes | Immuno-labelling followed by FACS analysis |
NOS2 Aliases: HEP-NOS, INOS, NOSA, NOS2 GeneCards | PubMed | DENV2 | RAW264.7 | Western blotting |
NOTCH4 Aliases: INT3 GeneCards | PubMed | DENV1, DENV2, DENV3 | Macrophages and Dendritic cells from differentiating Human PBMCs and CD4+ T cells | Real time RT-PCR |
NPR2 Aliases: AMDM, ANPRB, ANPb, ECDM, GUC2B, GUCY2B, NPRB, NPRBi GeneCards | PubMed | DENV2 | Huh7 | siRNA |
OASL Aliases: OASLd, TRIP-14, TRIP14, p59 OASL, p59-OASL, p59OASL GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
OCLN Aliases: BLCPMG, PPP1R115 GeneCards | PubMed | DENV4 | U937, MDCK | Immunofluorescence microscopy, Western blot, Transepithelial electrical resistance assay, Transmission electron microscopy, Vascular permeability assay |
OSM Aliases: GeneCards | PubMed | ADE DENV2 | THP-1 | cDNA array |
PECAM1 Aliases: CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM GeneCards | PubMed | DENV2 | Human Monocyte-derived immature dendritic cells, HUVEC | Protein array, In vitro permeability assay, In vivo vascular permeability enhancement assay, Immunofluorescence microscopy |
PECAM1 Aliases: CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM GeneCards | PubMed | DENV2 | EA.hy926 | Western blot, Confocal Laser Scanning Microscopy |
PLA2G7 Aliases: LDL-PLA2, LP-PLA2, PAFAD, PAFAH GeneCards | PubMed | DENV2 | Human neuroblastoma cell line SK-N-SH | PLA2 activity assay, Inhibition studies |
PLAT Aliases: T-PA, TPA GeneCards | PubMed | DENV2 | HUVEC | RT-PCR |
PPP1R15A Aliases: GADD34 GeneCards | PubMed | DENV2 | Human fibrosarcoma 2fTGH cells, MEF | Western blottting |
PROC Aliases: APC, PC, PROC1, THPH3, THPH4 GeneCards | PubMed | DENV2 | HUVEC | Western blot, Confocal microscopy, FACS, ELISA |
PSMB9 Aliases: LMP2, PSMB6i, RING12, beta1i GeneCards | PubMed | DENV2 | HepG2 | RT-PCR, Western blotting |
PTGER2 Aliases: EP2 GeneCards | PubMed | DENV2 | Human Monocyte-derived Dendritic cells | Inhibition studies |
PTGER4 Aliases: EP4, EP4R GeneCards | PubMed | DENV2 | Human Monocyte-derived Dendritic cells | Inhibition studies |
PTGS2 Aliases: COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 GeneCards | PubMed | DENV2 | Human Monocyte-derived Dendritic cells | RT-PCR, Western blot |
REL Aliases: C-Rel GeneCards | PubMed | DENV2 | RAW264.7 | Western blot, Luciferase reporter assay, Immunofluorescence microscopy, Inhibition studies |
RELB Aliases: I-REL, IREL, REL-B GeneCards | PubMed | DENV2 | Human neuroblastoma cell line SK-N-SH | NF-kB activation assay |
RELB Aliases: I-REL, IREL, REL-B GeneCards | PubMed | DENV2 | RAW264.7 | Western blot, Luciferase reporter assay, Immunofluorescence microscopy, Inhibition studies |
RELA Aliases: NFKB3, p65 GeneCards | PubMed | DENV1 | HepG2 | Immunofluorescence microscopy, Western blot, EMSA |
RELA Aliases: NFKB3, p65 GeneCards | PubMed | DENV2 | Human neuroblastoma cell line SK-N-SH | NF-kB activation assay |
RELA Aliases: NFKB3, p65 GeneCards | PubMed | DENV2 | 293A | Inhibition assay, Luciferase reporter gene assay |
RELA Aliases: NFKB3, p65 GeneCards | PubMed | DENV2 | HUVEC | Immunofluorscence microscopy |
RELA Aliases: NFKB3, p65 GeneCards | PubMed | DENV2 | Human Monocyte-derived Dendritic cells | EMSA |
RELA Aliases: NFKB3, p65 GeneCards | PubMed | DENV2 | Human bone-marrow–derived dendritic cells | Luciferase reporter assay, Immunofluorescence microscopy |
RELA Aliases: NFKB3, p65 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Enrichment analysis of transcription factors activating the DEGs |
RELA Aliases: NFKB3, p65 GeneCards | PubMed | DENV2 | RAW264.7 | Western blot, Luciferase reporter assay, Immunofluorescence microscopy, Inhibition studies |
RIPK1 Aliases: RIP, RIP-1, RIP1 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Quantitative real-time PCR |
RNASEK Aliases: GeneCards | PubMed | DENV2, DENV3, DENV4 | HeLa | Western blot, siRNA |
SELE Aliases: CD62E, ELAM, ELAM1, ESEL, LECAM2 GeneCards | PubMed | DENV2 | Human microvascular endothelial cells (HMVEC) | qRT-PCR, Western blot |
SOCS1 Aliases: CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3 GeneCards | PubMed | ADE DENV2 | THP-1 | Real-time RT-PCR |
SOCS3 Aliases: ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3 GeneCards | PubMed | ADE DENV2 | THP-1 | Real-time RT-PCR, Western blotting |
SOD2 Aliases: IPO-B, IPOB, MNSOD, MVCD6, Mn-SOD GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Quantitative real-time PCR |
SP1 Aliases: GeneCards | PubMed | ADE DENV2 | THP-1 | cDNA array |
SPP1 Aliases: BNSP, BSPI, ETA-1, OPN GeneCards | PubMed | DF, DHF | Patients sera | ELISA |
SQSTM1 Aliases: A170, FTDALS3, OSIL, PDB3, ZIP3, p60, p62, p62B GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Quantitative real-time PCR |
SQSTM1 Aliases: A170, FTDALS3, OSIL, PDB3, ZIP3, p60, p62, p62B GeneCards | PubMed | DENV2 | Huh7 | RT-qPCR, Confocal microscopy |
SRC Aliases: ASV, SRC1, THC6, c-SRC, p60-Src GeneCards | PubMed | DENV2 | Vero | Molecular modeling, Autodock Vina docking, Glide docking, In vitro Kinase inhibition assay, viral inhibition by RT-PCR |
STAT1 Aliases: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91 GeneCards | PubMed | DENV2 | Human Monocyte-derived dendritic cells | EMSA |
STAT1 Aliases: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91 GeneCards | PubMed | DENV2 | THP-1 | Antibody-dependent enhancement (ADE) infection assay, Western blotting |
STAT1 Aliases: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91 GeneCards | PubMed | DENV2 | HuH-7 | Western blotting |
STAT1 Aliases: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Enrichment analysis of transcription factors activating the DEGs |
STAT1 Aliases: CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91 GeneCards | PubMed | DENV2 | HUVEC | Western blotting |
SYK Aliases: p72-Syk GeneCards | PubMed | DENV2 | Human primary monocytes | Real-time PCR, Western blot |
TABP Aliases: ABP-278, ABP-280, AOI, FH1, FLN-B, FLN1L, LRS1, SCT, TABP, TAP GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | HepG2 | RT-PCR, Western blotting |
TAP1 Aliases: ABC17, ABCB2, APT1, D6S114E, PSF-1, PSF1, RING4, TAP1*0102N, TAP1N GeneCards | PubMed | DENV2 | HepG2 | RT-PCR, Western blotting |
TFPI Aliases: EPI, LACI, TFI, TFPI1 GeneCards | PubMed | DENV2 | HUVEC | RT-PCR |
THBD Aliases: AHUS6, BDCA3, CD141, THPH12, THRM, TM GeneCards | PubMed | DENV2 | HUVEC | RT-PCR |
THBD Aliases: AHUS6, BDCA3, CD141, THPH12, THRM, TM GeneCards | PubMed | DHF, DENV2 | THP-1, HUVEC, DHF Patient sera | RT-PCR, ELISA, FACS |
THBD Aliases: AHUS6, BDCA3, CD141, THPH12, THRM, TM GeneCards | PubMed | DF, DHF | Patients sera | ELISA |
TJP2 Aliases: C9DUPq21.11, DFNA51, DUP9q21.11, PFIC4, X104, ZO2 GeneCards | PubMed | DENV4 | U937, MDCK | Immunofluorescence microscopy, Western blot, Transepithelial electrical resistance assay, Transmission electron microscopy, Vascular permeability assay |
TKFC Aliases: DAK, NET45 GeneCards | PubMed | ADE DENV2 | THP-1 | Western blotting |
TNFRSF9 Aliases: 4-1BB, CD137, CDw137, ILA GeneCards | PubMed | DENV2 | HepG2 | siRNA |
TNFSF13B Aliases: BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, TNLG7A, ZTNF4 GeneCards | PubMed | DENV4 | HUVEC | ELISA |
TXNRD1 Aliases: GRIM-12, TR, TR1, TRXR1, TXNR GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Quantitative real-time PCR |
TYK2 Aliases: IMD35, JTK1 GeneCards | PubMed | DENV2 | Human Monocyte-derived dendritic cells | Western blotting |
TYROBP Aliases: DAP12, KARAP, PLOSL GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Human Macrophage, Mice | Western blot, Confocal microscopy, FACS, ELISA |
USP14 Aliases: TGT GeneCards | PubMed | DENV2 | 293T | Inhibition assay |
VCAM1 Aliases: CD106, INCAM-100 GeneCards | PubMed | DENV2 | HUVEC | FACs |
VCAM1 Aliases: CD106, INCAM-100 GeneCards | PubMed | Cord blood-derived mast cells (CBMCs), human mast cell-like line (HMC-1 ), HUVEC | ELISA | |
VCAM1 Aliases: CD106, INCAM-100 GeneCards | PubMed | DENV2 | Human microvascular endothelial cells (HMVEC) | qRT-PCR, Western blot |
VEGFC Aliases: Flt4-L, LMPH1D, VRP GeneCards | PubMed | Patients with and without plasma leakage | Patient blood samples | ELISA |
NRG1 Aliases: ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF-IT2, SMDF, NRG1 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
OAS1 Aliases: IFI-4, OIAS, OIASI GeneCards | PubMed | DENV2 | A549 | Over expression studies, Mutational studies |
OAS1 Aliases: IFI-4, OIAS, OIASI GeneCards | PubMed | DENV2 | HUVEC | RT-PCR |
OAS3 Aliases: p100, p100OAS GeneCards | PubMed | DENV2 | A549 | Over expression studies, Mutational studies |
OAS3 Aliases: p100, p100OAS GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
OPHN1 Aliases: ARHGAP41, MRX60, OPN1 GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
PACSIN3 Aliases: SDPIII GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
PARP1 Aliases: ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 GeneCards | PubMed | DENV2 | BHK | Western blotting |
PDIA2 Aliases: PDA2, PDI, PDIP, PDIR GeneCards | PubMed | DENV2 | HMEC-1 | siRNA, Inhibition studies, FACs, Confocal Microscopy |
PDIA3 Aliases: ER60, ERp57, ERp60, ERp61, GRP57, GRP58, HEL-S-269, HEL-S-93n, HsT17083, P58, PI-PLC GeneCards | PubMed | DENV2 | THP-1 | Proteomic analysis, siRNA, FACs, |
PFKFB3 Aliases: IPFK2, PFK2 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
PHF2 Aliases: CENP-35, GRC5, JHDM1E GeneCards | PubMed | DENV2 | Huh7 | siRNA |
PHF20 Aliases: C20orf104, GLEA2, HCA58, NZF, TDRD20A, TZP GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
PHOSPHO2 Aliases: GeneCards | PubMed | DENV2 | Huh7 | siRNA |
PIAS1 Aliases: DDXBP1, GBP, GU/RH-II, ZMIZ3 GeneCards | PubMed | ADE DENV2 | THP-1 | cDNA array |
PICK1 Aliases: PICK, PRKCABP GeneCards | PubMed | DENV2 | Huh7 | siRNA |
PIP4K2B Aliases: PI5P4KB, PIP5K2B, PIP5KIIB, PIP5KIIbeta, PIP5P4KB GeneCards | PubMed | DENV2 | Huh7 | siRNA |
PIP5K1A Aliases: GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
PKIB Aliases: PRKACN2 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
PKN3 Aliases: UTDP4-1 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
PLIN3 Aliases: M6PRBP1, PP17, TIP47 GeneCards | PubMed | Structure and sequence comparison | ||
PLK3 Aliases: CNK, FNK, PRK GeneCards | PubMed | DENV2 | Huh7 | siRNA |
PMAIP1 Aliases: APR, NOXA GeneCards | PubMed | DENV2 | HepG2 | Real time PCR |
PMAIP1 Aliases: APR, NOXA GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Quantitative real-time PCR |
PML Aliases: MYL, PP8675, RNF71, TRIM19 GeneCards | PubMed | DENV2 | A549 | siRNA, Real time RT-PCR |
PNLIPRP1 Aliases: PLRP1 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
PPP2R2A Aliases: B55A, B55ALPHA, PR52A, PR55A GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
PRG4 Aliases: CACP, HAPO, JCAP, MSF, SZP GeneCards | PubMed | DENV2 | Huh7 | siRNA |
PRKCD Aliases: ALPS3, CVID9, MAY1, PKCD, nPKC-delta GeneCards | PubMed | DENV2 | Huh7 | siRNA |
PRKDC Aliases: DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, IMD26, XRCC7, p350 GeneCards | PubMed | DENV2 | Huh7, 293T | Chemoproteomic profiling, siRNA |
PRKRA Aliases: DYT16, HSD14, PACT, RAX GeneCards | PubMed | DENV2, DENV3 | HepG2, K562 | Knockout studies |
PRKRA Aliases: DYT16, HSD14, PACT, RAX GeneCards | PubMed | DENV1 | HEK293-derived cell line FLP-IN T Rex (Invitrogen) | Overexpression studies, siRNA studies |
PRKRA Aliases: DYT16, HSD14, PACT, RAX GeneCards | PubMed | DENV1, DENV2, DENV3 | A549, HepG2 | Western blotting, Immunofluorescence microscopy, siRNA |
PRKRA Aliases: DYT16, HSD14, PACT, RAX GeneCards | PubMed | DENV2 | HuH-7 | Real-time RT-PCR, Western blotting, ISRE-luciferase reporter assay |
PRKRA Aliases: DYT16, HSD14, PACT, RAX GeneCards | PubMed | DENV2 | A549 | Western blot |
PRR12 Aliases: KIAA1205 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
RAB11B Aliases: H-YPT3 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
RAB29 Aliases: RAB7L, RAB7L1 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
RAB29 Aliases: RAB7L, RAB7L1 GeneCards | PubMed | DENV2 | Huh-7.5, 293T | siRNA |
RAB3A Aliases: GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
RAB3D Aliases: D2-2, GOV, RAB16, RAD3D GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
RAB5A Aliases: RAB5 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
RAB8A Aliases: MEL, RAB8 GeneCards | PubMed | DENV2 | HepG2 | FACS, Real time RT-PCR, Indirect Immunofluorescence staining |
RAB8B Aliases: GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
RAC1 Aliases: MIG5, Rac-1, TC-25, p21-Rac1 GeneCards | PubMed | DENV2 | HMEC-1 | Virus binding assay, FACS, Time-lapse fluorescent microscopy |
RIPK2 Aliases: CARD3, CARDIAK, CCK, GIG30, RICK, RIP2 GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
RNASEL Aliases: PRCA1, RNS4 GeneCards | PubMed | DENV2, DENV3 | HepG2, K562 | Knockout studies |
RNASEL Aliases: PRCA1, RNS4 GeneCards | PubMed | DENV2 | A549 | Over expression studies, Mutational studies |
ROCK1 Aliases: P160ROCK, ROCK-I GeneCards | PubMed | DENV2 | ECV304 | Indirect Immunofluorescence Staining, Western blotting |
RPSA Aliases: 37LRP, 67LR, ICAS, LAMBR, LAMR1, LBP, LBP/p40, LRP, LRP/LR, NEM/1CHD4, SA, lamR, p40 GeneCards | PubMed | DENV1 | Vero | Virus overlay protein binding assay, Nondenaturing and denaturing gel systems with mass spectrometry |
RPSA Aliases: 37LRP, 67LR, ICAS, LAMBR, LAMR1, LBP, LBP/p40, LRP, LRP/LR, NEM/1CHD4, SA, lamR, p40 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Porcine kidney cell line PS Clone D cell line | Virus overlay protein binding assay, MALDI-TOF MS |
RSAD2 Aliases: 2510004L01Rik, cig33, cig5, vig1 GeneCards | PubMed | DENV1 | HEK293-derived cell line FLP-IN T Rex (Invitrogen) | Overexpression studies, siRNA studies |
RSAD2 Aliases: 2510004L01Rik, cig33, cig5, vig1 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Quantitative real-time PCR |
RSAD2 Aliases: 2510004L01Rik, cig33, cig5, vig1 GeneCards | PubMed | DENV2 | HUVEC | RT-PCR |
SCARB1 Aliases: CD36L1, CLA-1, CLA1, HDLQTL6, SR-BI, SRB1 GeneCards | PubMed | DENV2 | Vero, AD-293, Huh-7, HepG2 | Co-immunoprecipitation, siRNA, FACs analysis after virus absorption |
SDC2 Aliases: CD362, HSPG, HSPG1, SYND2 GeneCards | PubMed | DENV2 | 293 | siRNA, virus binding and infectivity assays, RT-PCR |
SEC61B Aliases: GeneCards | PubMed | DENV2 | Huh7 | siRNA |
SERPINE1 Aliases: PAI, PAI-1, PAI1, PLANH1 GeneCards | PubMed | DF, DHF and DSS | Serial blood samples | PAI-1 antigen assay |
SHPK Aliases: CARKL, SHK GeneCards | PubMed | DENV2 | Huh7 | siRNA |
SIK3 Aliases: L19, QSK, SIK-3 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
SLC2A1 Aliases: CSE, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT-1, GLUT1, GLUT1DS, HTLVR, PED GeneCards | PubMed | DENV2 | Primary human foreskin fibroblasts (HFFs) | Western blotting, qRT-PCR |
SLC5A12 Aliases: SMCT2 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
SMAD7 Aliases: CRCS3, MADH7, MADH8 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
SPHK1 Aliases: SPHK GeneCards | PubMed | DENV2 | HUVEC | Sphingosine kinase 1 activity assay |
STAT2 Aliases: ISGF-3, P113, STAT113 GeneCards | PubMed | DENV2 | Huh7, AG129 | ISG inhibition assays |
STAT2 Aliases: ISGF-3, P113, STAT113 GeneCards | PubMed | DENV2 | A549 | qRT-PCR, siRNA |
STAT3 Aliases: ADMIO, APRF, HIES GeneCards | PubMed | DENV2 | Human Monocyte-derived dendritic cells | EMSA |
STAT3 Aliases: ADMIO, APRF, HIES GeneCards | PubMed | DENV2 | HepG2 | EMSA, Western blotting |
STAU1 Aliases: PPP1R150, STAU GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
STK32B Aliases: HSA250839, STK32, STKG6, YANK2 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
STMN1 Aliases: C1orf215, LAP18, Lag, OP18, PP17, PP19, PR22, SMN GeneCards | PubMed | DENV2 | EAhy926 | qRT-PCR, Westerblotting |
STYK1 Aliases: NOK, SuRTK106 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
SYNGR1 Aliases: GeneCards | PubMed | DENV2 | Huh7 | siRNA |
SYNJ1 Aliases: INPP5G, PARK20 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
SYNJ2 Aliases: INPP5H GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
TAZ Aliases: BTHS, CMD3A, EFE, EFE2, G4.5, LVNCX, Taz1 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
TBX20 Aliases: ASD4 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
TESK2 Aliases: GeneCards | PubMed | DENV2 | Huh7 | siRNA |
TF Aliases: PRO1557, PRO2086QTL1, TF GeneCards | PubMed | Patients sera | Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry, ELISA, Western blotting | |
TIMD4 Aliases: SMUCKLER, TIM4 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | 293T, CHO745, Cos-7, A549, Vero, Huh7 5.1 | Cell-Binding Assay, siRNA, Immunofluroscence assay |
TIRAP Aliases: BACTS1, Mal, MyD88-2, wyatt GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
TJP1 Aliases: ZO-1 GeneCards | PubMed | DENV2 | EA.hy926 | Western blot, Confocal Laser Scanning Microscopy |
TLR2 Aliases: CD282, TIL4 GeneCards | PubMed | DENV2 | Patient blood samples, PBMCs | FACS |
TLR3 Aliases: CD283, IIAE2 GeneCards | PubMed | DENV2 | 293, THP1, U937 | FACS, Real time RT-PCR, knockdown assay |
TLR3 Aliases: CD283, IIAE2 GeneCards | PubMed | DENV1 | Macrophages, Huh-7 and shRIG-I cells | RT-PCR, siRNA, Western blot, ELISA, Immunofluorescence microscopy |
TLR3 Aliases: CD283, IIAE2 GeneCards | PubMed | DENV2 | HepG2 | RT-PCR, Immunofluorescence microscopy |
TLR4 Aliases: ARMD10, CD284, TLR-4, TOLL GeneCards | PubMed | DENV2 | Patient blood samples, PBMCs | FACS |
TLR6 Aliases: CD286 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
TNF Aliases: DIF-alpha, TNFA, TNFSF2, TNF GeneCards | PubMed | DF Grade I, DF Grade II | Serial blood samples | ELISA |
TNF Aliases: DIF-alpha, TNFA, TNFSF2, TNF GeneCards | PubMed | DENV2 | THP-1 | Antibody-dependent enhancement (ADE) infection assay, ELISA |
TNF Aliases: DIF-alpha, TNFA, TNFSF2, TNF GeneCards | PubMed | DENV2 | HUVECs | qRT-PCR |
TNF Aliases: DIF-alpha, TNFA, TNFSF2, TNF GeneCards | PubMed | DENV2, DENV3, DENV4 | Serum of DF and DHF patient | ELISA |
TNF Aliases: DIF-alpha, TNFA, TNFSF2, TNF GeneCards | PubMed | DENV2 | Human bone-marrow–derived dendritic cells | qPCR |
TNF Aliases: DIF-alpha, TNFA, TNFSF2, TNF GeneCards | PubMed | DENV4 | U937, MDCK | BD cytometric bead array |
TNF Aliases: DIF-alpha, TNFA, TNFSF2, TNF GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Inhibition followed by Fluidigm BioMark high throughput qPCR assay |
TNF Aliases: DIF-alpha, TNFA, TNFSF2, TNF GeneCards | PubMed | DENV2 | RAW264.7 | ELISA, Western blotting |
TNFSF10 Aliases: APO2L, Apo-2L, CD253, TL2, TRAIL GeneCards | PubMed | DENV2 | Human plasmacytoid dendritic cells extracted from Healthy controls and Dengue patients | Flow Cytometry, Three dimension microscopy and immunofluorescence |
TP53 Aliases: BCC7, LFS1, P53, TRP53 GeneCards | PubMed | DENV1 | BHK, Huh-7, Vero | TUNEL assay, FACS, Western blot, Mutational analysis |
TP53 Aliases: BCC7, LFS1, P53, TRP53 GeneCards | PubMed | DENV1 | p53-deficient H1299, Huh7 | siRNA, Real time RT-PCR |
TP53 Aliases: BCC7, LFS1, P53, TRP53 GeneCards | PubMed | DENV2 | Human Monocyte derived Dendritic cells | Enrichment analysis of transcription factors activating the DEGs |
TRAPPC10 Aliases: EHOC-1, EHOC1, GT334, TMEM1, TRS130, TRS30 GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
TREM1 Aliases: CD354, TREM-1 GeneCards | PubMed | Monocytes, Neutrophils and Sera of dengue patients | Flow Cytometry | |
TRIM56 Aliases: RNF109 GeneCards | PubMed | DENV2 | 293, HeLa | Over expression studies, siRNA |
TTK Aliases: CT96, ESK, MPH1, MPS1, MPS1L1, PYT GeneCards | PubMed | DENV2 | Huh7 | siRNA |
TUBE1 Aliases: TUBE, dJ142L7.2 GeneCards | PubMed | DENV2 | ECV304 | DD-RT-PCR, Real time PCR |
TYRO3 Aliases: BYK, Dtk, Etk-2, RSE, Rek, Sky, Tif GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | 293T, CHO745, Cos-7, A549, Vero, Huh7 5.1 | Cell-Binding Assay, siRNA, Immunofluroscence assay |
UBE2E3 Aliases: UBCH9, UbcM2 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
UGP2 Aliases: UDPG, UDPGP, UDPGP2, UGP1, UGPP1, UGPP2, pHC379 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
UHMK1 Aliases: KIS, KIST, P-CIP2 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
USP13 Aliases: ISOT3, IsoT-3 GeneCards | PubMed | DENV2 | 293T | siRNA, Immunoprecipitation-immunoblotting analysis, qRT-PCR |
VEGFA Aliases: MVCD1, VEGF, VPF GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | HPMEC-ST1.6R | Microbead-based Bio-Plex immunoassay |
VIM Aliases: CTRCT30, HEL113 GeneCards | PubMed | DENV2 | ECV304 | Indirect Immunofluorescence Staining, Western blotting |
VTN Aliases: V75, VN, VNT GeneCards | PubMed | Patients sera | Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry, ELISA, Western blotting | |
WASF2 Aliases: IMD2, SCAR2, WASF4, WAVE2, dJ393P12.2 GeneCards | PubMed | DENV1, DENV2, DENV3, DENV4 | Huh7, HepG2 | siRNA |
XAF1 Aliases: BIRC4BP, HSXIAPAF1, XIAPAF1 GeneCards | PubMed | DENV2 | HUVECs, EA.hy926 | Microarray, quantitative reverse transcriptase–polymerase chain reaction (qRT-PCR), Western blot analysis, Colocalization by confocal microscopy, Coimmunoprecipitation, overexpression analysis, knockdown analysis |
XAF1 Aliases: BIRC4BP, HSXIAPAF1, XIAPAF1 GeneCards | PubMed | DENV2 | HUVEC, EA.hy926 | Knockdown analysis, expression analysis |
XAF1 Aliases: BIRC4BP, HSXIAPAF1, XIAPAF1 GeneCards | PubMed | DENV2 | HUVEC, EA.hy926 | Western blotting |
XBP1 Aliases: TREB-5, TREB5, XBP-1, XBP2 GeneCards | PubMed | DENV1, DENV2 | A549 | Western blot, RT-PCR, inhibition assays |
XBP1 Aliases: TREB-5, TREB5, XBP-1, XBP2 GeneCards | PubMed | DENV2 | Huh-7.5, 293T | siRNA |
XBP1 Aliases: TREB-5, TREB5, XBP-1, XBP2 GeneCards | PubMed | DENV2 | Human fibrosarcoma 2fTGH cells, MEF | Western blottting |
XBP1 Aliases: TREB-5, TREB5, XBP-1, XBP2 GeneCards | PubMed | DENV2 | HepG2 | Real time PCR |
XIAP Aliases: API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 GeneCards | PubMed | DENV2 | HUVECs, EA.hy926 | Microarray, quantitative reverse transcriptase–polymerase chain reaction (qRT-PCR), Western blot analysis, Colocalization by confocal microscopy, Coimmunoprecipitation, overexpression analysis, knockdown analysis |
ZBTB41 Aliases: FRBZ1, ZNF924 GeneCards | PubMed | DENV2 | Huh7 | siRNA |
ZNF91 Aliases: HPF7, HTF10 GeneCards | PubMed | DENV2 | Huh7 | siRNA |